TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression
Y Huang, Y Xie, PW Abel, P Wei, J Plowman… - Biochemical …, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with irreversible
loss of lung tissue and function. Myofibroblasts in the lung are key cellular mediators of IPF …
loss of lung tissue and function. Myofibroblasts in the lung are key cellular mediators of IPF …
Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis
P Wei, Y Xie, PW Abel, Y Huang, Q Ma, L Li, J Hao… - Cell death & …, 2019 - nature.com
Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of
idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to …
idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to …
The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis
X Chen, C Shi, C Wang, W Liu, Y Chu, Z Xiang, K Hu… - Scientific reports, 2017 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal fibrotic lung disease
characterized by profound changes in stem cell differentiation, epithelial cell phenotypes …
characterized by profound changes in stem cell differentiation, epithelial cell phenotypes …
miR-338-3p blocks TGFβ-induced myofibroblast differentiation through the induction of PTEN
AR Rackow, JL Judge, CF Woeller… - … of Physiology-Lung …, 2022 - journals.physiology.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease. The pathogenesis of
IPF is not completely understood. However, numerous genes are associated with the …
IPF is not completely understood. However, numerous genes are associated with the …
The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis
C Liang, X Li, L Zhang, D Cui, X Quan… - … and Molecular Pathology, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial fibrotic lung disease with an
undefined etiology and no effective treatments. By binding to cell surface receptors …
undefined etiology and no effective treatments. By binding to cell surface receptors …
IPF-fibroblast Erk1/2 activity is independent from microRNA cluster 17-92 but can be inhibited by treprostinil through DUSP1
S Blumer, L Fang, WC Chen, P Khan, K Hostettler… - Cells, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive terminal lung disease, and therapies aim
to block fibrosis. Fibroblast proliferation is controlled by C/EBP-β, microRNA cluster 17-92 …
to block fibrosis. Fibroblast proliferation is controlled by C/EBP-β, microRNA cluster 17-92 …
MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fatal disorder resulting from the progressive
remodeling of lungs, with no known effective treatment. Although transforming growth factor …
remodeling of lungs, with no known effective treatment. Although transforming growth factor …
miR‐19a,‐19b, and‐26b mediate CTGF expression and pulmonary fibroblast differentiation
YC Chen, BC Chen, CC Yu, SH Lin… - Journal of cellular …, 2016 - Wiley Online Library
Although microRNA (miRNA) dysregulation with intracellular signaling cascade disruption
has been demonstrated in the pathophysiology of pulmonary fibrosis, the relationship …
has been demonstrated in the pathophysiology of pulmonary fibrosis, the relationship …
Expression analysis of microRNAs and mRNAs in myofibroblast differentiation of lung resident mesenchymal stem cells
C Wang, H Cao, S Gu, C Shi, X Chen, X Han - Differentiation, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a serious lung disease that involved the myofibroblast
differentiation of lung resident mesenchymal stem cells (LR-MSCs). However, the specific …
differentiation of lung resident mesenchymal stem cells (LR-MSCs). However, the specific …
Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition
Idiopathic pulmonary fibrosis (IPF) is one of the most common and severe interstitial lung
diseases. Epithelial-to-mesenchymal transition (EMT) is a process whereby epithelial cells …
diseases. Epithelial-to-mesenchymal transition (EMT) is a process whereby epithelial cells …
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