Repairing cartilage defects using thermosensitive hydrogels is an attractive treatment
strategy, but the poor mechanical properties and limited understanding of the interactions …

Regeneration of injured articular cartilage is limited by low early-stage recruitment of stem
cells and insufficient chondrogenic differentiation. Hydrogels are widely used to repair …

Cartilage has limited self-repair ability, leading to osteoarthritis postinjury and ultimately
physical disability in people. In addition, cartilage injury is accompanied by loss of …

Chondral defects pose a great challenge for clinicians to manage owing to the limited
capacity for self-healing. Various traditional approaches have been adopted for the repair of …

Intra-articular injection of anti-inflammatory drugs can be a promising strategy for recovery of
injured articular cartilage. We prepared a series of injectable thermo-sensitive composite …

Hydrogels are attractive for cartilage tissue engineering because of their high plasticity and
similarity with the native cartilage matrix. However, one critical drawback of hydrogels for …

Because of poor self-repair capacity, the repair of cartilage defect is always a great
challenge in clinical treatment. In vitro cartilage regeneration provides a potential strategy for …

Cartilage defects can be difficult to heal, potentially leading to complications such as
osteoarthritis. Recently, a tissue engineering approach that uses scaffolds and growth …

Biophysical properties of the desired biomimetic scaffolds, such as porosity and elasticity,
have been proven associated with the efficacy of cartilage regeneration. In this work, the …

Background Unlike bone tissue, articular cartilage regeneration has not been very
successful and has many challenges ahead. We have previously developed injectable …