The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being
obesity, age, environmental variables, and genetic predisposition. The available evidence …

The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being
obesity, age, environmental variables, and genetic predisposition. The available evidence …

Osteoarthritis (OA) is a chronic musculoskeletal disease characterised by the destruction of
articular cartilage, synovial inflammation and bone remodelling. Disease aetiology is …

Background: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors
are strongly associated with its development; however, recently it has been observed that …

Osteoarthritis (OA) is a prevalent disease of articular joints and primarily characterized by
degradation and calcification of articular cartilage. Presently, no effective treatment other …

Introduction Osteoarthritis (OA) is a chronic musculoskeletal disease characterized by
progressive loss of joint function. Historically, it has been characterized as a disease caused …

Osteoarthritis (OA) is a complicated disease with both hereditary and environmental causes.
Despite an increase in reports of possible OA risk loci, it has become clear that genetics is …

Genome-wide expression and methylation profiling reveal candidate genes in osteoarthritis
Page 1 Clinical and Experimental Rheumatology 2017 Clinical and Experimental …

Osteoarthritis (OA) is the most prevalent chronic age-related arthritic disease that mainly
affects the diarthrodial joints. Nevertheless, there is no treatment currently available that can …

Osteoarthritis (OA) is a major clinical problem across the world, in part due to the lack of
disease-modifying drugs resulting, to a significant degree, from our incomplete …