Maternal depression and adverse neighbourhood conditions during pregnancy are associated with gestational epigenetic age deceleration

AA Appleton, B Lin, EM Kennedy, EA Holdsworth - Epigenetics, 2022 - Taylor & Francis
Gestational epigenetic age (GEA) acceleration and deceleration can indicate developmental
risk and may help elucidate how prenatal exposures lead to offspring outcomes. Depression …

Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use

BG McKenna, CL Hendrix, PA Brennan, AK Smith… - Epigenetics, 2021 - Taylor & Francis
Previous studies suggest epigenetic alterations may contribute to the association between
maternal prenatal depression and adverse offspring outcomes. Developmental researchers …

Maternal childhood adversity and infant epigenetic aging: Moderation by restless sleep during pregnancy

DW Sosnowski, DM Rojo‐Wissar… - Developmental …, 2024 - Wiley Online Library
Maternal exposure to childhood adversity is associated with detrimental health outcomes
throughout the life span and may have implications for offspring. Evidence links maternal …

Maternal psychosocial risk factors and child gestational epigenetic age in a South African birth cohort study

N Koen, MJ Jones, RT Nhapi, MT Lake… - Translational …, 2021 - nature.com
Accelerated epigenetic aging relative to chronological age has been found to be associated
with higher risk of mortality in adults. However, little is known about whether and how in …

Maternal adversity and epigenetic age acceleration predict heightened emotional reactivity in offspring: Implications for intergenerational transmission of risk

BG McKenna, J Choi, PA Brennan, A K. Knight… - Research on Child and …, 2023 - Springer
Black American women are disproportionately exposed to adversities that may have an
intergenerational impact on mental health. The present study examined whether maternal …

The epigenetic clock at birth: associations with maternal antenatal depression and child psychiatric problems

A Suarez, J Lahti, D Czamara, M Lahti-Pulkkinen… - Journal of the American …, 2018 - Elsevier
Objective Maternal antenatal depression may compromise the fetal developmental milieu
and contribute to individual differences in aging and disease trajectories in later life. We …

[HTML][HTML] Maternal prenatal anxiety and the fetal origins of epigenetic aging

MG McGill, I Pokhvisneva, AS Clappison… - Biological …, 2022 - Elsevier
Background The fetal origins of mental health is a well-established framework that currently
lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal …

Placental accelerated aging in antenatal depression

H Saeed, J Wu, M Tesfaye, KL Grantz… - American Journal of …, 2024 - Elsevier
BACKGROUND Antenatal maternal depression is associated with poor pregnancy
outcomes and long-term effects on the offspring. Previous studies have identified links …

Placental epigenetic gestational aging in relation to maternal sociodemographic factors and smoking among infants born extremely preterm: a descriptive study

J Clark, CM Bulka, CL Martin, K Roell, HP Santos… - Epigenetics, 2022 - Taylor & Francis
Social determinants of health (SDoH) are defined as the conditions in which people are
born, grow, live, work, and age. The distribution of these conditions is influenced by …

Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants

S Katrinli, AK Smith, SS Drury, J Covault, JD Ford… - Epigenetics, 2023 - Taylor & Francis
Pregnancy can exacerbate or prompt the onset of stress-related disorders, such as post-
traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity …