Inflammatory and anti‐inflammatory cytokines in chronic heart failure: potential therapeutic implications

P Aukrust, L Gullestad, T Ueland, JK Damås… - Annals of …, 2005 - Taylor & Francis
Persistent inflammation, involving increased levels of inflammatory cytokines, seems to play
a pathogenic role in chronic heart failure (HF) by influencing heart contractility, inducing …

Inflammatory cytokines in heart failure: mediators and markers

L Gullestad, T Ueland, LE Vinge, A Finsen, A Yndestad… - Cardiology, 2012 - karger.com
Evidence from both experimental and clinical trials indicates that inflammatory mediators are
of importance in the pathogenesis of chronic heart failure (HF) contributing to cardiac …

Role of inflammation in the progression of heart failure

A Yndestad, JK Damås, E Øie, T Ueland… - Current cardiology …, 2007 - Springer
Chronic heart failure (HF) is a disorder characterized in part by immune activation and
inflammation. Thus, patients with HF have elevated levels of a number of inflammatory …

Systemic inflammation in heart failure–the whys and wherefores

A Yndestad, J Kristian Damås, E Øie, T Ueland… - Heart failure …, 2006 - Springer
Patients with chronic heart failure (HF) are characterized by systemic inflammation, as
evident by raised circulating levels of several inflammatory cytokines with increasing levels …

Review of trials in chronic heart failure showing broad-spectrum anti-inflammatory approaches

L Gullestad, P Aukrust - The American journal of cardiology, 2005 - Elsevier
Accumulating evidence indicates that inflammatory mediators are important in the
pathogenesis of chronic heart failure (CHF), contributing to cardiac remodeling and …

The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure

A Briasoulis, E Androulakis, T Christophides… - Heart failure …, 2016 - Springer
Chronic inflammation underlies a variety of seemingly unrelated conditions including
coronary artery disease. The interest in exploring the role of inflammation in heart failure …

Inflammatory mediators in chronic heart failure: an overview

SD Anker, S von Haehling - Heart, 2004 - heart.bmj.com
Chronic heart failure (CHF) represents a major public health burden, and its prognosis is
comparable to that of different malignant diseases. Our understanding of CHF has …

Various aspects of inflammation in heart failure

M Dutka, R Bobiński, I Ulman-Włodarz, M Hajduga… - Heart failure …, 2020 - Springer
Despite significant advances in the prevention and treatment of heart failure (HF), the
prognosis in patients who have been hospitalised on at least one occasion due to …

Inflammatory cytokines, immune cells, and organ interactions in heart failure

H Li, C Chen, DW Wang - Frontiers in physiology, 2021 - frontiersin.org
Despite mounting evidence demonstrating the significance of inflammation in the
pathophysiological mechanisms of heart failure (HF), most large clinical trials that target the …

Proinflammatory cytokines in heart failure: double-edged swords

M Hedayat, MJ Mahmoudi, NR Rose, N Rezaei - Heart failure reviews, 2010 - Springer
Increased circulating and intracardiac levels of proinflammatory cytokines have been
associated with chronic heart failure. Following an initial insult, the increased production of …