• Enrolling patients with ARDS in clinical trials using the American-European Consensus
Conference definition1 ignores the heterogeneity of the disease. In pathological terms, the …

Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome.
Understanding of the complex pathways involved in lung injury pathogenesis, resolution …

Mortality in the acute respiratory distress syndrome (ARDS) ranges from 40 to 60%. Recent
studies have suggested that this rate is decreasing, but they lack explanations for the …

The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary
edema and hypoxemia associated with a variety of etiologies, carries a high morbidity rate …

ContextThe acute lung injury and acute respiratory distress syndrome are critical illnesses
associated with significant morbidity and mortality. Mechanical ventilation is the cornerstone …

Critical care providers are frequently confronted with the challenges of managing patients
with acute respiratory distress syndrome (ARDS). Although noninvasive options like high …

Acute respiratory distress syndrome represents a complex syndrome with considerable
morbidity and mortality, for which there exist no targeted treatment strategies. However …

Objective: The objective of this study was to review known clinical predictors and biologic
markers of adverse clinical outcomes in acute lung injury (ALI) and acute respiratory distress …

The results of recent clinical trials have raised more questions. Further study of the
inflammatory response, surfactant regulation, and the cellular impact of mechanical …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are acute life-
threatening forms of hypoxemic respiratory failure. ALI/ARDS patients require intensive care …