POS0850 SHORT-TERM EFFICACY AND TOLERABILITY OF BARNIDIPINE AS CALCIUM CHANNEL BLOCKER IN RAYNAUD'S PHENOMENON SECONDARY TO …

R Bixio, F Mastropaolo, M Appolloni, D Bertelle… - 2024 - ard.bmj.com
Background: Raynaud's phenomenon (RP) represents one of the main features and causes
of comorbidity in patients with Systemic Sclerosis (SSc). Dihydropyridine calcium-channel …

POS1244 RESULTS OF A PHASE 2A STUDY OF CILNIDIPINE, A NOVEL DAILY ORAL CALCIUM CHANNEL BLOCKER WITH N-CHANNEL SELECTIVITY, FOR THE …

A Sternlicht, M Shanahan, E Morton, E Briggs, I Hunt… - 2023 - ard.bmj.com
Background Systemic Sclerosis (SSc) is a rare autoimmune disease with fibrosis, changes
in the skin, vasculature, joints and internal organs. Diffuse disease involves lung, heart and …

Calcium‐channel blockers for Raynaud's phenomenon in systemic sclerosis

AE Thompson, B Shea, V Welch, D Fenlon… - Arthritis & …, 2001 - Wiley Online Library
Objective Most patients with systemic sclerosis (SSc) have Raynaud's phenomenon (RP),
which is often more severe than idiopathic RP. This study was a meta‐analysis to determine …

Response to Dr Bolland's eLetter: Strontium and cardiovascular events

JY Reginster - Annals of the Rheumatic Diseases, 2014 - ard.bmj.com
The work carried out by the authors on calcium and the cardiovascular risk is of primary
importance. 1 We thank the authors for questions and comments on the Strontium ranelate …

POS0394 AMINAPHTONE SHORT-TERM TREATMENT REDUCES TGF-BETA PLASMA LEVELS IN SYSTEMIC SCLEROSIS PATIENTS WITH SECONDARY …

A Sulli, S Soldano, E Gotelli, A Cere, R Campitiello… - 2024 - ard.bmj.com
Background: Aminaphtone (3-Methyl-1, 4-dioxo-1, 4-dihydro-naphthalen-2-y4-amino-
benzoate) is a chemical vasoactive compound licensed to treat microvascular disorders [1] …

Bosentan therapy for patients with severe Raynaud's phenomenon in systemic sclerosis

ME Hettema, D Zhang, H Bootsma… - Annals of the …, 2007 - ard.bmj.com
Raynaud's phenomenon (RP) is present in more than 95% of patients with systemic
sclerosis (SSc). Its frequency and severity in combination with the presence of digital ulcers …

FRI0265 Selexipag in Raynaud's Phenomenon Secondary To Systemic Sclerosis: A Randomised, Placebo-Controlled, Phase II Study

CP Denton, Έ Hachulla, G Riemekasten, A Schwarting… - 2016 - ard.bmj.com
Background Raynaud9s phenomenon (RP) occurs in> 95% of patients (pts) with systemic
sclerosis (SSc) and contributes to digital ischaemia that may lead to digital ulcers (DUs) and …

Increased prevalence of ocular glaucomatous abnormalities in systemic sclerosis

AYK Chan, DTL Liu - Annals of the Rheumatic Diseases, 2005 - ard.bmj.com
We read with interest the paper by Hall and Buchbinder, 1 which discussed the importance
of accurate needle placement guided by imaging techniques in the therapeutic response to …

AB1457 ABNORMAL STANDARD BLOOD CARDIAC BIOMARKERS DO NOT IDENTIFY CARDIOVASCULAR MRI ABNORMALITIES IN PATIENTS WITH …

HN Cheema, RR Shukla, R Dumitru, S Plein, M Buch - 2024 - ard.bmj.com
Background: Cardiovascular MRI (CMR) abnormalities can be detected in people with
rheumatoid arthritis (RA) and systemic sclerosis (SSc) in the absence of cardiac symptoms …

AB0291 PROGNOSTIC VALUE OF LATE GADOLINIUM ENHANCEMENT ON CARDIAC MAGNETIC RESONANCE IMAGING IN SYSTEMIC LUPUS …

AJ Velvet, S Vohra, T David, B Keavney, I Bruce… - 2021 - ard.bmj.com
Background: Cardiac Magnetic Resonance Imaging (CMRI) with Late Gadolinium
Enhancement (LGE) has an established value in the diagnostic and prognostic assessment …