Downregulation of umbilical cord blood levels of miR-374a in neonatal hypoxic ischemic encephalopathy

AM Looney, BH Walsh, G Moloney, S Grenham… - The Journal of …, 2015 - Elsevier
Objective To investigate the expression profile of microRNA (miRNA) in umbilical cord blood
from infants with hypoxic ischemic encephalopathy (HIE). Study design Full-term infants with …

MicroRNA expression profiles as diagnostic and prognostic biomarkers of perinatal asphyxia and hypoxic-ischaemic encephalopathy

I Winkler, T Heisinger, M Hammerl, E Huber… - Neonatology, 2022 - karger.com
Introduction: Perinatal asphyxia is a leading cause of neonatal death. Up to one-third of
asphyxiated neonates suffer from hypoxic-ischaemic encephalopathy (HIE) with substantial …

[HTML][HTML] Temporally altered miRNA expression in a piglet model of hypoxic ischemic brain injury

S Casey, K Goasdoue, SM Miller, GP Brennan… - Molecular …, 2020 - Springer
Hypoxic ischemic encephalopathy (HIE) is the most frequent cause of acquired infant brain
injury. Early, clinically relevant biomarkers are required to allow timely application of …

Validation of altered umbilical cord blood microRNA expression in neonatal hypoxic-ischemic encephalopathy

MP O'Sullivan, AM Looney, GM Moloney… - JAMA …, 2019 - jamanetwork.com
Importance Neonatal hypoxic-ischemic encephalopathy (HIE) remains a significant cause of
neurologic disability. Identifying infants suitable for therapeutic hypothermia (TH) within a …

[HTML][HTML] A study of microRNAs from dried blood spots in newborns after perinatal asphyxia: a simple and feasible biosampling method

V Ponnusamy, O Kapellou, E Yip, J Evanson… - Pediatric …, 2016 - nature.com
Background: The potential of microRNAs (miRNAs) as bedside biomarkers in selecting
newborns with hypoxic-ischemic encephalopathy (HIE) for neuroprotection has yet to be …

MicroRNA therapeutic targets in neonatal hypoxic–ischemic brain injury: a narrative review

ES Peeples - Pediatric Research, 2023 - nature.com
Neonatal hypoxic–ischemic brain injury (HIBI) is a devastating injury resulting from impaired
blood flow and oxygen delivery to the brain at or around the time of birth. Despite the use of …

Temporal profile of circulating microRNAs after global hypoxia-ischemia in newborn piglets

HT Garberg, MU Huun, LO Baumbusch… - Neonatology, 2017 - karger.com
Background: There is a lack of reliable biomarkers that can identify and grade acute hypoxic-
ischemic encephalopathy in newborns. MicroRNAs (miRNA) are short, non-coding strands …

The role of microRNAs in newborn brain development and hypoxic ischaemic encephalopathy

V Ponnusamy, PK Yip - Neuropharmacology, 2019 - Elsevier
Neonates can develop hypoxic-ischaemic encephalopathy (HIE) due to lack of blood supply
or oxygen, resulting in a major cause of death and disability among term newborns …

Regulatory mechanism of MicroRNA-30b on neonatal hypoxic-ischemic encephalopathy (HIE)

W Wang, L Jia - Journal of Stroke and Cerebrovascular Diseases, 2021 - Elsevier
Objective This study is to investigate the role of microRNA (miR)-30b in the pathogenesis of
hypoxic-ischemic encephalopathy (HIE) in neonates. Methods Totally 26 cases of neonatal …

[HTML][HTML] MicroRNAs as biomarkers of brain injury in neonatal encephalopathy: an observational cohort study

F Dakroub, F Kobeissy, S Mondello, Z Yang, H Xu… - Scientific reports, 2024 - nature.com
Neonatal Encephalopathy (NE) is a major cause of lifelong disability and neurological
complications in affected infants. Identifying novel diagnostic biomarkers in this population …