Intracranial atherosclerotic disease (ICAD) is a major cause of stroke and yet there are no
proven effective treatments for it. Medical therapy has been associated with a high rate of …

Background Patients with symptomatic stenosis of intradural arteries are at high risk for
subsequent stroke. Since the SAMMPRIS trial, stenting is no longer recommended as …

Introduction The SAMMPRIS trial suggested that aggressive treatment was superior to
endovascular stenting in patients with severe symptomatic intracranial atherosclerotic …

Background Patients with high-grade symptomatic intracranial stenosis (≥ 70%) have an
increased risk of recurrent stroke despite medical treatment with antiplatelet or anticoagulant …

regardless of the use of warfarin or aspirin. 1 Patients presenting with a lesion that is 70%
appear to be most vulnerable with a 1-year risk of 23% for a subsequent ipsilateral event. 2 …

Intracranial arterial stenosis (ICAS) is a common cause of stroke, and the risk of ischemic
stroke from a stenotic intracranial artery remains high despite best medical therapy (BMT) …

Intracranial atherosclerosis (ICAS) is a major cause of stroke worldwide. Although
approximately 12% of White patients with a history of acute ischemic stroke or transient …

Background Intracranial atherosclerotic stenosis (ICAS) is associated with high risk of
recurrent strokes despite best medical management (MM). We aimed to synthesize the …

Background In the Stenting and Aggressive Medical Management for Preventing Recurrent
Stroke in Intracranial Stenosis (SAMMPRIS) trial, 19.1% of ischemic strokes occurred out of …

BACKGROUND AND PURPOSE: Intracranial angioplasty and stent placement are used to
treat intracranial atherosclerotic disease. The 2 interventions have not been directly …