[HTML][HTML] Gene regulation by nucleoporins and links to cancer
A Köhler, E Hurt - Molecular cell, 2010 - cell.com
Nuclear pore complexes (NPCs) composed of∼ 30 individual nucleoporins form huge
macromolecular assemblies in the nuclear envelope, through which bidirectional cargo …
macromolecular assemblies in the nuclear envelope, through which bidirectional cargo …
Functional interactions between nucleoporins and chromatin
Y Liang, MW Hetzer - Current opinion in cell biology, 2011 - Elsevier
As the gatekeepers of the eukaryotic cell nucleus, nuclear pore complexes (NPCs) mediate
all molecular trafficking between the nucleoplasm and the cytoplasm. In recent years …
all molecular trafficking between the nucleoplasm and the cytoplasm. In recent years …
Nuclear pore complexes guardians of the nuclear genome
M Capelson, C Doucet… - Cold Spring Harbor …, 2010 - symposium.cshlp.org
Eukaryotic cell function depends on the physical separation of nucleoplasmic and
cytoplasmic components by the nuclear envelope (NE). Molecular communication between …
cytoplasmic components by the nuclear envelope (NE). Molecular communication between …
The role of nuclear pores in gene regulation, development and disease
M Capelson, MW Hetzer - EMBO reports, 2009 - embopress.org
Nuclear‐pore complexes (NPCs) are large protein channels that span the nuclear envelope
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
Nuclear pore proteins in regulation of chromatin state
TM Kuhn, M Capelson - Cells, 2019 - mdpi.com
Nuclear pore complexes (NPCs) are canonically known to regulate nucleocytoplasmic
transport. However, research efforts over the last decade have demonstrated that NPCs and …
transport. However, research efforts over the last decade have demonstrated that NPCs and …
The nuclear pore complex in cell type-specific chromatin structure and gene regulation
J Sun, Y Shi, E Yildirim - Trends in genetics, 2019 - cell.com
Nuclear pore complex (NPC)-mediated nucleocytoplasmic trafficking is essential for key
cellular processes, such as cell growth, cell differentiation, and gene regulation. The NPC …
cellular processes, such as cell growth, cell differentiation, and gene regulation. The NPC …
Nuclear pore proteins and the control of genome functions
A Ibarra, MW Hetzer - Genes & development, 2015 - genesdev.cshlp.org
Nuclear pore complexes (NPCs) are composed of several copies of∼ 30 different proteins
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
Dynamics and diverse functions of nuclear pore complex proteins
G Chatel, B Fahrenkrog - Nucleus, 2012 - Taylor & Francis
Nuclear pore complexes (NPCs) are best known for their central role in controlling the
molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from …
molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from …
Nuclear pore proteins and cancer
S Xu, MA Powers - Seminars in cell & developmental biology, 2009 - Elsevier
Nucleocytoplasmic trafficking of macromolecules, a highly specific and tightly regulated
process, occurs exclusively through the nuclear pore complex. This immense structure is …
process, occurs exclusively through the nuclear pore complex. This immense structure is …
The functional versatility of the nuclear pore complex proteins
M Hezwani, B Fahrenkrog - Seminars in cell & developmental biology, 2017 - Elsevier
Over the past few decades, it is increasingly evident that nucleoporins are multi-functional
proteins that are not only pivotal for the formation of the nuclear pore complex. They also …
proteins that are not only pivotal for the formation of the nuclear pore complex. They also …