Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts
Circular RNAs (circRNAs) encompass a widespread and conserved class of RNAs, which
are generated by back-splicing of downstream 5′ to upstream 3′ splice sites. CircRNAs …
are generated by back-splicing of downstream 5′ to upstream 3′ splice sites. CircRNAs …
[HTML][HTML] Translation and functional roles of circular RNAs in human cancer
M Lei, G Zheng, Q Ning, J Zheng, D Dong - Molecular cancer, 2020 - Springer
Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed
loops through backsplicing. Recent methodologies have enabled in-depth characterization …
loops through backsplicing. Recent methodologies have enabled in-depth characterization …
[HTML][HTML] Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas
Y Wang, C Wu, Y Du, Z Li, M Li, P Hou, Z Shen, S Chu… - Molecular cancer, 2022 - Springer
Circular RNAs (circRNAs) are classified as noncoding RNAs because they are devoid of a
5'end cap and a 3'end poly (A) tail necessary for cap-dependent translation. However …
5'end cap and a 3'end poly (A) tail necessary for cap-dependent translation. However …
[HTML][HTML] A universal approach to investigate circRNA protein coding function
D Mo, X Li, CA Raabe, D Cui, JF Vollmar… - Scientific Reports, 2019 - nature.com
Circular RNAs (circRNAs) are an emerging class of RNA molecules that have been linked to
human diseases and important regulatory pathways. Their functional roles are still under …
human diseases and important regulatory pathways. Their functional roles are still under …
[HTML][HTML] Molecular mechanisms of circular RNA translation
HJ Hwang, YK Kim - Experimental & Molecular Medicine, 2024 - nature.com
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs without a 5′ cap
structure and a 3′ poly (A) tail typically present in linear mRNAs of eukaryotic cells …
structure and a 3′ poly (A) tail typically present in linear mRNAs of eukaryotic cells …
CircPro: an integrated tool for the identification of circRNAs with protein-coding potential
Circular RNAs (circRNAs), a novel class of endogenous RNAs, are widespread in eukaryotic
cells. Emerging roles in diverse biological processes suggest that circRNA is a promising …
cells. Emerging roles in diverse biological processes suggest that circRNA is a promising …
[HTML][HTML] Extensive translation of circular RNAs driven by N6-methyladenosine
Extensive pre-mRNA back-splicing generates numerous circular RNAs (circRNAs) in human
transcriptome. However, the biological functions of these circRNAs remain largely unclear …
transcriptome. However, the biological functions of these circRNAs remain largely unclear …
Translatable circRNAs and lncRNAs: Driving mechanisms and functions of their translation products
S Kong, M Tao, X Shen, S Ju - Cancer letters, 2020 - Elsevier
Long non-coding RNA (lncRNAs) are functional RNA segments longer than 200
nucleotides, which are considered a redundant transcriptional product. Recently, lncRNAs …
nucleotides, which are considered a redundant transcriptional product. Recently, lncRNAs …
[HTML][HTML] Structured elements drive extensive circular RNA translation
The human genome encodes tens of thousands circular RNAs (circRNAs) with mostly
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
The emerging functions and roles of circular RNAs in cancer
S Qu, Z Liu, X Yang, J Zhou, H Yu, R Zhang, H Li - Cancer letters, 2018 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that
undergo a specific backsplicing from pre-mRNA. With the application of high-throughput …
undergo a specific backsplicing from pre-mRNA. With the application of high-throughput …