Peroxisome proliferator activated receptor γ agonists suppress TNFα-induced ICAM-1 expression by endothelial cells in a manner potentially dependent on inhibition …

Y Jung, S Song, C Choi - Immunology letters, 2008 - Elsevier
In this study, we investigated the anti-inflammatory effect of various peroxisome proliferator
activated receptor gamma (PPARγ) agonists (15-deoxy-Δ12, 14-prostaglandin J2 …

Pemafibrate, a novel selective peroxisome proliferator-activated receptor α modulator, reduces plasma eicosanoid levels and ameliorates endothelial dysfunction in …

K Suto, D Fukuda, M Shinohara… - … of Atherosclerosis and …, 2021 - jstage.jst.go.jp
Aims: Various pathological processes related to diabetes cause endothelial dysfunction.
Eicosanoids derived from arachidonic acid (AA) have roles in vascular regulation. Fibrates …

Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: a possible role for PPARγ in endothelial …

K Kato, H Satoh, Y Endo, D Yamada… - Biochemical and …, 1999 - Elsevier
The effect of peroxisome proliferator-activated receptor (PPAR) γ activators,
thiazolidinediones, on plasminogen activator type 1 (PAI-1) was examined in cultured …

Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor β agonists via the phosphatidyl-inositol-3 kinase-Akt pathway

R Jimenez, M Sanchez, MJ Zarzuelo, M Romero… - … of Pharmacology and …, 2010 - ASPET
Peroxisome proliferator-activated receptor β/δ (PPAR-β) is a ligand-activated transcription
factor belonging to the nuclear hormone receptor superfamily that regulates the transcription …

PPARδ and PGC1α act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress

F Ali, NS Ali, A Bauer, JJ Boyle… - Cardiovascular …, 2010 - academic.oup.com
Aims Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear
receptor superfamily of ligand-activated transcriptional regulators. PPARδ has an …

Peroxisome proliferator-activated receptor-γ–mediated effects in the vasculature

SZ Duan, MG Usher, RM Mortensen - Circulation research, 2008 - Am Heart Assoc
Peroxisome proliferator-activated receptor (PPAR)-γ is a nuclear receptor and transcription
factor in the steroid superfamily. PPAR-γ agonists, the thiazolidinediones, are clinically used …

NAD (P) H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR) α-mediated cardiovascular effects

M Newaz, A Blanton, P Fidelis, A Oyekan - … Research/Fundamental and …, 2005 - Elsevier
Activation of peroxisome proliferator activated receptor (PPAR) α and its protective role in
cardiovascular function has been reported but the exact mechanism (s) involved is not clear …

Telmisartan protects against diabetic vascular complications in a mouse model of obesity and type 2 diabetes, partially through peroxisome proliferator activated …

K Toyama, T Nakamura, K Kataoka, O Yasuda… - Biochemical and …, 2011 - Elsevier
Experimental and clinical data support the notion that peroxisome proliferator-activated
receptor γ (PPARγ) activation is associated with anti-atherosclerosis as well as anti-diabetic …

[HTML][HTML] Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation

K Ohshima, M Mogi, M Horiuchi - International journal of vascular …, 2012 - hindawi.com
Vascular inflammation plays a crucial role in atherosclerosis, and its regulation is important
to prevent cerebrovascular and coronary artery disease. The inflammatory process in …

Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension

MJ Zarzuelo, M Gomez-Guzman… - Cardiovascular …, 2013 - academic.oup.com
Aims We analysed the chronic effects of the peroxisome proliferator-activated receptor β/δ
(PPAR-β) agonist GW0742 on the renin-independent hypertension induced by …