Thes physical state of human papillomavirus 16 DNAxs in cervical carcinoma and cervical intraepithelial neoplasia

M Fukushima, Y Yamakawa, S Shimano… - Cancer, 1990 - Wiley Online Library
Cervical carcinomas and cervical intraepithelial neoplasias (CIN) were analyzed for the
presence of human papillomavirus (HPV) DNA using Southern blot hybridization. of the five …

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

AP Cullen, R Reid, M Campion, AT Lörincz - Journal of virology, 1991 - Am Soc Microbiol
The integration of human papillomavirus (HPV) DNA into the human genome has been
generally accepted as a characteristic of malignant lesions. To gain a better understanding …

Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions

BC Das, JK Sharma… - Journal of General …, 1992 - microbiologyresearch.org
Integration of human papillomavirus (HPV) DNA into the host cell genome is believed to be
essential for malignant progression. However unambiguous detection of the physical state of …

Both episomal and integrated forms of human papillomavirus type 16 are involved in invasive cervical cancers

T Matsukura, S Koi, M Sugase - Virology, 1989 - Elsevier
The form of human papillomavirus type 16 (HPV 16) DNA in specimens of invasive cervical
cancer was investigated. High molecular, tandem repeats of viral sequences were detected …

Detection of human papillomavirus type 16 DNA and evidence for integration into the cell DNA in cervical dysplasia

H Shirasawa, Y Tomita, K Kubota… - Journal of general …, 1986 - microbiologyresearch.org
The presence of human papillomavirus (HPV) type 16 DNA in biopsies from precancerous
lesions and from early lesions of human cervical cancer, and the integration of virus DNA …

Physical state and biological activity of human papillomavirus genomes in precancerous lesions of the female genital tract

H Lehn, LL Villa, F Marziona… - Journal of General …, 1988 - microbiologyresearch.org
The DNA of distinct human papillomaviruses (HPVs) is regularly detected in the majority of
human cervical carcinomas. In contrast to benign HPV-induced genital lesions, where the …

Analysis of HPV16, 18, 31, and 35 DNA in pre-invasive and invasive lesions of the uterine cervix.

L Pirami, V Giache, A Becciolini - Journal of clinical pathology, 1997 - jcp.bmj.com
AIMS: To analyse the physical state of different human papillomavirus (HPV) DNAs in 55
intraepithelial and invasive HPV associated cervical neoplasms. METHODS: Restriction …

Differences in the integration pattern and episomal forms of human papillomavirus type 16 DNA found within an invasive cervical neoplasm and its metastasis

D Galehouse, E Jenison, A Delucia - Virology, 1992 - Elsevier
Human papillomavirus (H PV) type 16 DNA was found in three separate neoplastic lesions
within a female patient. The physical state of the viral DNA in each lesion was determined by …

Analysis by multiplex PCR of the physical status of human papillomavirus type 16 DNA in cervical cancers

M Yoshinouchi, A Hongo, K Nakamura… - Journal of clinical …, 1999 - Am Soc Microbiol
Integration of human papillomavirus (HPV) DNA occurs early in cancer development and is
an important event in malignant transformation of cervical cancer. Integration of HPVs …

Analysis of integrated human papillomavirus type 16 DNA in cervical cancers: amplification of viral sequences together with cellular flanking sequences

M Wagatsuma, K Hashimoto, T Matsukura - Journal of virology, 1990 - Am Soc Microbiol
We have isolated four clones of integrated human papillomavirus type 16 (HPV-16) DNA
from four different primary cervical cancer specimens. All clones were found to be …