FY* B polymorphism is caused by a missense point mutation at NT 129 of the Duffy gene,
changing Gly42 in Fya to Asp42 in Fyb. 18–20, 22 In Fy (a–b–) people, most of whom are …

The molecular basis of the three major alleles (Fya/Fyb/Fy) of the Duffy (FY) blood group
system has recently been established but the Fyx phenotype associated with weak …

Background: Because limited studies have shown that the Duffy genotype is not accurately
reflected by the erythrocyte phenotype, we used PCR-RFLP to determine the true FY1 and …

ACKR1, located on chromosome 1q23. 2, is the gene that encodes a glycoprotein
expressing the Duffy blood group antigens. This gene is transcribed in two mRNA variants …

Results The melting point of FY* A was 63ºC and of FY* B was 55ºC, whereas the allele
without mutation at the promoter region had a melting point of 64ºC and the FY* B silent …

Background and objectives Duffy blood group phenotypes can be predicted by genotyping
for single nucleotide polymorphisms (SNP s) responsible for the Fya/Fyb polymorphism, for …

Duffy blood group antigens are carried on a glycoprotein that is predicted to pass through
the erythrocyte membrane seven times and is a promiscuous chemokine receptor. The Fy …

Background Duffy (FY) blood group genotyping is important in transfusion medicine
because Duffy alloantibodies are associated with delayed hemolytic transfusion reactions …

The Duffy blood group has five antigenic specificities, Fya, Fyb, Fy3, Fy4, and Fy5, that are
part of, or related to, the system. The first four antigens are under the genetic control of a …

BACKGROUND: In the Duffy blood group system, the null phenotype Fy (a–b–) has been
classically associated with a mutated GATA box, while the Fyx phenotype weak Fyb is …