A novel gene panel for prediction of lymph-node metastasis and recurrence in patients with thyroid cancer

EML Ruiz, T Niu, M Zerfaoui, M Kunnimalaiyaan… - Surgery, 2020 - Elsevier
Background Although well-differentiated papillary thyroid cancer may remain indolent,
lymph node metastases and the recurrence rates are approximately 50% and 20 …

Development and validation of prediction models for papillary thyroid cancer structural recurrence using machine learning approaches

H Wang, C Zhang, Q Li, T Tian, R Huang, J Qiu, R Tian - BMC cancer, 2024 - Springer
Background Although papillary thyroid cancer (PTC) patients are known to have an
excellent prognosis, up to 30% of patients experience disease recurrence after initial …

A miRNA-based prognostic model to trace thyroid cancer recurrence

EA Toraih, MS Fawzy, B Ning, M Zerfaoui, Y Errami… - Cancers, 2022 - mdpi.com
Simple Summary Some thyroid tumors elected for surveillance remain indolent, while others
progress. The mechanism responsible for this difference is poorly understood, making it …

Prognostic lncRNA, miRNA, and mRNA signatures in papillary thyroid carcinoma

K Wang, J Xu, L Zhao, S Liu, C Liu, L Zhang - Frontiers in genetics, 2020 - frontiersin.org
The current focus in the treatment of papillary thyroid carcinoma (PTC) is tumor progression.
The aim of this study was to build RNA-based classifiers and develop a comprehensive …

Foundation one genomic interrogation of thyroid cancers in patients with metastatic disease requiring systemic therapy

NM Iñiguez-Ariza, S Jasim, MM Ryder… - The Journal of …, 2020 - academic.oup.com
Context Clinical applications of genomic assessment of thyroid cancers are rapidly evolving.
Objectives, Design, and Setting We studied tumor samples from patients with imminently …

Evaluation of clinicopathological and molecular parameters on disease recurrence of papillary thyroid cancer patient: A retrospective observational study

S Sorrenti, G Carbotta, FM Di Matteo, A Catania… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid cancer (PTC) patients are staged according to the Tumor-
Node-Metastasis staging system (TNM). This work was aimed at comparing the usefulness …

Identification of a five-gene signature and establishment of a prognostic nomogram to predict progression-free interval of papillary thyroid carcinoma

M Wu, H Yuan, X Li, Q Liao, Z Liu - Frontiers in endocrinology, 2019 - frontiersin.org
Background: The incidence of papillary thyroid carcinoma (PTC) is high and increasing
worldwide. Although prognosis is relatively good, it is important to select the minority of …

Identification of a recurrence signature and validation of cell infiltration level of thyroid cancer microenvironment

L Zhang, Y Wang, X Li, Y Wang, K Wu, J Wu… - Frontiers in …, 2020 - frontiersin.org
Though many patients with thyroid cancer may be indolent, there are still about 50% lymph
node metastases and 20% the recurrence rates. There is still no ideal method to predict its …

[HTML][HTML] miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and meta-analysis

T Wang, H Xu, M Qi, S Yan, X Tian - Oncotarget, 2018 - ncbi.nlm.nih.gov
Thyroid cancer (TC) is the most common endocrine malignancy, with an incidence
continuing to grow every year. Although thyroid cancer as a whole is generally indolent and …

The genomic landscape of thyroid cancer tumourigenesis and implications for immunotherapy

A Singh, J Ham, JW Po, N Niles, T Roberts, CS Lee - Cells, 2021 - mdpi.com
Thyroid cancer is the most prevalent endocrine malignancy that comprises mostly indolent
differentiated cancers (DTCs) and less frequently aggressive poorly differentiated (PDTC) or …