[HTML][HTML] Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy
S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …
and functions in elderly people. It is accompanied by physical frailty, functional disability …
[HTML][HTML] Molecular mechanism and pathogenesis of sarcopenia: An overview
Sarcopenia involves a progressive age-related decline of skeletal muscle mass and
strength/function [1]. This muscle loss is associated with increased risk of adverse health …
strength/function [1]. This muscle loss is associated with increased risk of adverse health …
[HTML][HTML] Cellular senescence in sarcopenia: possible mechanisms and therapeutic potential
Y He, W Xie, H Li, H Jin, Y Zhang, Y Li - Frontiers in Cell and …, 2022 - frontiersin.org
Aging promotes most degenerative pathologies in mammals, which are characterized by
progressive decline of function at molecular, cellular, tissue, and organismal levels and …
progressive decline of function at molecular, cellular, tissue, and organismal levels and …
Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy
Sarcopenia, the age-related loss of skeletal muscle mass, is a significant public health
concern that continues to grow in relevance as the population ages. Certain conditions have …
concern that continues to grow in relevance as the population ages. Certain conditions have …
Mouse models of sarcopenia: classification and evaluation
W Xie, M He, D Yu, Y Wu, X Wang, S Lv… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia is a progressive and widespread skeletal muscle disease that is related to an
increased possibility of adverse consequences such as falls, fractures, physical disabilities …
increased possibility of adverse consequences such as falls, fractures, physical disabilities …
[HTML][HTML] Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia
Sarcopenia, the age-related loss of skeletal muscle mass and function, affects 5–13% of
individuals aged over 60 years. While rodents are widely-used model organisms, which …
individuals aged over 60 years. While rodents are widely-used model organisms, which …
[HTML][HTML] Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update
GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
[HTML][HTML] Murine models of atrophy, cachexia, and sarcopenia in skeletal muscle
M Romanick, LDV Thompson… - Biochimica et Biophysica …, 2013 - Elsevier
With the extension of life span over the past several decades, the age-related loss of muscle
mass and strength that characterizes sarcopenia is becoming more evident and thus, has a …
mass and strength that characterizes sarcopenia is becoming more evident and thus, has a …
[HTML][HTML] Biochemical pathways of sarcopenia and their modulation by physical exercise: a narrative review
Aging is a complex process characterized by progressive multisystem derangement
predisposing individuals to increased risk of developing negative health outcomes …
predisposing individuals to increased risk of developing negative health outcomes …
[HTML][HTML] Age-related dysfunction in proteostasis and cellular quality control in the development of sarcopenia
Sarcopenia is a debilitating skeletal muscle disease that accelerates in the last decades of
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …