Frailty is a complex syndrome affecting a growing sector of the global population as medical
developments have advanced human mortality rates across the world. Our current …

An age-dependent decline in skeletal muscle mass, strength, and endurance during the
aging process is a physiological development, but several factors may exacerbate this …

By the year 2050, individuals over the age of 65 years will comprise 20% of the US
population. Loss of muscle mass and strength is common in this age group and it is …

Sarcopenia, the progressive loss of muscle mass with age, is characterized by a
deterioration of muscle quantity and quality leading to a gradual slowing of movement and a …

Skeletal muscle aging is associated with a significant loss of skeletal muscle strength and
power (ie, dynapenia), muscle mass and quality of life, a phenomenon known as …

Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

Age-related loss of the skeletal muscle and its function is known as sarcopenia. Definition
and diagnostic criteria for sarcopenia have been outlined as consensus statements from …

Age-related skeletal muscle sarcopenia has been extensively studied and smooth muscle
sarcopenia has been recently described, but age-related cardiac sarcopenia has not been …

Sarcopenia has a significant negative impact on healthspan in the elderly and effective
pharmacologic interventions remain elusive. We have previously demonstrated that …

Sarcopenia is characterized by a loss of muscle mass and function that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries. At the intracellular level …