Sarcopenia, the progressive loss of muscle mass and strength, is one of the major health
issues in older adults, given its high prevalence accompanied by huge clinical and …

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with
increasing age, being a major component in the development of frailty. Current knowledge …

Simple Summary With old age, the strength and size of our muscles worsens with time,
affecting our ability to carry out daily activities. Muscle wasting may be more dangerous for …

Introduction: Sarcopenia, the age-related loss of skeletal muscle mass and function, is a
global health problem that contributes to the development of physical disability, morbidity …

Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …

Muscle loss during aging and disuse is a highly prevalent and disabling condition, but
knowledge about cellular pathways mediating muscle atrophy is still limited. Given the …

The slow and continuous loss of muscle mass that progresses with aging is defined as
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …

In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …

We here review the loss of muscle function and mass (sarcopenia) in the framework of
human healthspan and lifespan, and mechanisms involved in aging. The rapidly changing …

Our knowledge of the significance of sarcopenia in old age is limited by a lack of
epidemiologic data, an incomplete assessment of the pathophysiologic consequences of …