A six-month double-blind, placebo-controlled, randomized clinical trial of duloxetine for the treatment of fibromyalgia

AS Chappell, LA Bradley, C Wiltse… - … Journal of General …, 2009 - Taylor & Francis
Objective: Assess the efficacy of duloxetine 60/120 mg (N= 162) once daily compared with
placebo (N= 168) in the treatment of patients with fibromyalgia, during six months of …

Efficacy and safety of duloxetine 30 mg/d in patients with fibromyalgia: a randomized, double-blind, placebo-controlled study

LM Arnold, S Zhang, BA Pangallo - The Clinical journal of pain, 2012 - journals.lww.com
Objectives: To evaluate the efficacy and safety of duloxetine 30 mg/d in adults with
fibromyalgia. Methods: This 12-week, randomized, double-blind, placebo-controlled study …

Efficacy of duloxetine in patients with fibromyalgia: pooled analysis of 4 placebo-controlled clinical trials

LM Arnold, DJ Clauw, MM Wohlreich… - … care companion to …, 2009 - psychiatrist.com
Objective: To investigate the efficacy of duloxetine in the treatment of pain and improvement
in functional impairment and quality of life in patients with fibromyalgia from a pooled …

A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia

AS Chappell, G Littlejohn, DK Kajdasz… - The clinical journal …, 2009 - journals.lww.com
Objectives Evaluate the efficacy and safety of duloxetine at doses up to 120 mg once daily in
patients with fibromyalgia. Methods This was a phase 3, 60-week study, which included an 8 …

Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: results from a 6-month, randomized, double-blind …

IJ Russell, PJ Mease, TR Smith, DK Kajdasz… - Pain, 2008 - Elsevier
The primary objectives of this study were to assess the efficacy and safety of duloxetine for
reducing pain severity in fibromyalgia patients with or without current major depressive …

Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia

PJ Mease, IJ Russell, DK Kajdasz, CG Wiltse… - Seminars in arthritis and …, 2010 - Elsevier
OBJECTIVES: To assess the long-term safety, tolerability, and efficacy of duloxetine in
patients with fibromyalgia. METHODS: We report results from the 6-month extension phases …

Comparisons of the efficacy and safety of duloxetine for the treatment of fibromyalgia in patients with versus without major depressive disorder

LM Arnold, JI Hudson, F Wang… - The Clinical journal …, 2009 - journals.lww.com
Objectives To investigate whether comorbid major depressive disorder (MDD) influenced
the efficacy and safety of duloxetine in treating fibromyalgia (FM). Methods This was a post …

A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder

LM Arnold, A Rosen, YL Pritchett, DN D'Souza… - Pain, 2005 - Elsevier
This was a 12-week, randomized, double-blind, placebo-controlled trial to assess the
efficacy and safety of duloxetine, a selective serotonin and norepinephrine reuptake …

Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial

LM Arnold, D Clauw, F Wang, J Ahl, PJ Gaynor… - The Journal of …, 2010 - jrheum.org
Objective. To investigate the efficacy of flexible dose duloxetine 60–120 mg/day on changes
in fibromyalgia (FM) symptoms assessed by the Patient Global Impression of Improvement …

Safety and tolerability of duloxetine in the treatment of patients with fibromyalgia: pooled analysis of data from five clinical trials

EHS Choy, PJ Mease, DK Kajdasz, MM Wohlreich… - Clinical …, 2009 - Springer
The purpose of this report is to describe the overall safety profile of both short-and longer-
term duloxetine treatment of fibromyalgia. Data from four double-blind, randomized, placebo …