Objective To assess the efficacy and safety of duloxetine, a serotonin and norepinephrine
reuptake inhibitor, in subjects with primary fibromyalgia, with or without current major …

Background: To assess the efficacy (in particular, in pain, functional impairment, and quality
of life) and safety and tolerability (incidence of adverse events, discontinuation rates …

Objectives: The objective of this systematic review was to assess the analgesic efficacy of
duloxetine (DLX) for fibromyalgia (FM) and find out which dosage between 60 mg/d DLX …

Objective. To review the use of duloxetine, a new selective serotonin and norepinephrine
reuptake inhibitor (SNRI), and other antidepressants in the treatment of patients with …

The objective of this paper is to better understand the relationship of pain and mood in
patients with fibromyalgia and comorbid major depressive disorder (MDD). Pooled data from …

This article presents a brief review of the physiologic abnormalities seen in fibromyalgia,
current theories of widespread pain, and treatment options, including emerging therapeutics …

Introduction Fibromyalgia is characterized by widespread pain and is often accompanied by
accessory symptoms. There are limited treatment options for this condition in Japan …

Introduction The optimal dose of duloxetine in the management of fibromyalgia remains still
controversial. Therefore, a systematic review and meta-analysis to investigate efficacy and …

Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and
Drug Administration for the treatment of fibromyalgia and painful diabetic neuropathy at …

Objective: This meta‐analysis compared efficacy (pain response) of drugs that are licensed
or commonly used in the treatment of fibromyalgia. A meta‐analysis of safety measured via …