Background: Depression is underdiagnosed in the primary care setting. Physical symptoms
such as aches, pains, and gastrointestinal disturbance are frequently associated with major …

Objective: Major depressive disorder (MDD) is a significant public health concern and
challenges health care providers to intervene with appropriate treatment. This article …

Study Design. This was a randomized, double-blind, placebo-controlled clinical trial.
Objective. To assess the efficacy and safety of duloxetine in the treatment of chronic low …

Objective: To evaluate duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine,
on improvement of emotional and painful physical symptoms. Design: Randomized, double …

Painful physical symptoms are common features of major depressive disorder and may be
the presenting complaints in primary care settings. The effect of the dual serotonin (5-HT) …

Abstract Treatment recommendations for fibromyalgia (FM) include a range of predominantly
pharmacological treatment options designed to ensure the maintenance of symptoms and …

Background: Fibromyalgia is a chronic neurological condition characterized by widespread
pain. The effectiveness of current pharmacological treatments is limited. However, several …

The results of two 6-month long, randomized, double-blind, controlled trials (RCT) of the
anticonvulsant pregabalin [5] and the balanced serotonin–norepinephrine re-uptake …

Objective: To evaluate the efficacy and safety of duloxetine in the treatment of chronic pain
due to osteoarthritis of the knee. Methods: This was a 13‐week, randomized, double‐blind …

BACKGROUND: Patients with fibromyalgia (FM) rate stiffness as one of the most
troublesome symptoms of the disorder. However, there are few published studies that have …