Clinical experience with duloxetine in the management of chronic musculoskeletal pain. A focus on osteoarthritis of the knee

JP Brown, LJ Boulay - Therapeutic advances in …, 2013 - journals.sagepub.com
Duloxetine is a serotonin and norepinephrine reuptake inhibitor (SNRI) with central nervous
system activity. Its analgesic efficacy in central pain is putatively related to its influence on …

Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression

MJ Detke, Y Lu, DJ Goldstein, RK McNamara… - Journal of psychiatric …, 2002 - Elsevier
Existing therapies for major depressive disorder (MDD) have either limited efficacy and/or
poor tolerability. The present study examined the effects of duloxetine, a potent and …

[HTML][HTML] Randomized, double-blind, placebo-controlled phase III trial of duloxetine monotherapy in Japanese patients with chronic low back pain

S Konno, N Oda, T Ochiai, L Alev - 2016 - journals.lww.com
Study Design. A 14-week, randomized, double-blind, multicenter, placebo-controlled study
of Japanese patients with chronic low back pain (CLBP) who were randomized to either …

[HTML][HTML] Efficacy and safety of duloxetine versus placebo in adolescents with juvenile fibromyalgia: results from a randomized controlled trial

HP Upadhyaya, LM Arnold, K Alaka, M Qiao… - Pediatric …, 2019 - Springer
Background Currently, there are no medications approved for the treatment of juvenile
fibromyalgia (JFM). We evaluated the safety and efficacy of duloxetine 30/60 mg once daily …

[HTML][HTML] Saffron (Crocus sativus) versus duloxetine for treatment of patients with fibromyalgia: A randomized double-blind clinical trial

M Shakiba, E Moazen-Zadeh, AA Noorbala… - Avicenna journal of …, 2018 - ncbi.nlm.nih.gov
Objective: Saffron was found efficient and safe in treatment of neuropsychiatric disorders, in
particular depression. We compared the efficacy of saffron with duloxetine in treatment of …

Duloxetine plasma concentrations and its effectiveness in the treatment of nonorganic chronic pain in the orofacial region

Y Kobayashi, W Nagashima, T Tokura… - Clinical …, 2017 - journals.lww.com
Objective The purpose of this study was to examine the relationship between the pain-
relieving effects of duloxetine and its plasma concentrations in patients with burning mouth …

Duloxetine for the treatment of major depressive disorder: a closer look at efficacy and safety data across the approved dose range

CH Mallinckrodt, A Prakash, AC Andorn… - Journal of psychiatric …, 2006 - Elsevier
OBJECTIVE: This analysis focuses on efficacy and safety data obtained from studies of
duloxetine for the treatment of major depressive disorder (MDD) within the approved dose …

Antidepressants in the treatment of fibromyalgia

C Moret, M Briley - Neuropsychiatric disease and treatment, 2006 - Taylor & Francis
Fibromyalgia syndrome is a chronic disease of widespread and debilitating pain whose
cause is unknown and whose risk factors are poorly understood. It is often comorbid with …

Duloxetine 60 mg for chronic low back pain: post hoc responder analysis of double-blind, placebo-controlled trials

L Alev, S Fujikoshi, A Yoshikawa, H Enomoto… - Journal of pain …, 2017 - Taylor & Francis
Introduction Duloxetine has demonstrated efficacy in chronic low back pain (CLBP). We
examined the predictors of response to duloxetine for CLBP. Patients and methods This was …

Treatment patterns associated with ACR-recommended medications in the management of fibromyalgia in the United States

Y Liu, C Qian, M Yang - Journal of managed care & specialty pharmacy, 2016 - jmcp.org
BACKGROUND: Fibromyalgia (FM) affects up to 6% of US adults, resulting in a significant
burden on the health care system and poor quality of life for patients. Duloxetine, pregabalin …