3-Phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: Synthesis and Biological Activity of a Novel Group of Potential Antifungal Drugs
M Pour, M Špulák, V Buchta, P Kubanová… - Journal of medicinal …, 2001 - ACS Publications
3-(Substituted phenyl)-5-acyloxymethyl-2 H, 5 H-furan-2-ones related to the natural product
(−) incrustoporine were synthesized and their in vitro antifungal activity evaluated. The …
(−) incrustoporine were synthesized and their in vitro antifungal activity evaluated. The …
3-Phenyl-5-methyl-2H, 5H-furan-2-ones: tuning antifungal activity by varying substituents on the phenyl ring
M Pour, M Špulák, V Balšánek, J Kuneš… - Bioorganic & medicinal …, 2000 - Elsevier
A series of racemic 3-phenyl-5-methyl-2H, 5H-furan-2-ones related to a natural product,(−)
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …
Synthesis and structure–antifungal activity relationships of 3-aryl-5-alkyl-2, 5-dihydrofuran-2-ones and their carbanalogues: Further refinement of tentative …
M Pour, M Špulák, V Balšánek, J Kuneš… - Bioorganic & medicinal …, 2003 - Elsevier
Two series of 3-(substituted phenyl)-5-alkyl-2, 5-dihydrofuran-2-ones related to a natural
product,(−) incrustoporine, were synthesized and their in vitro antifungal activity evaluated …
product,(−) incrustoporine, were synthesized and their in vitro antifungal activity evaluated …
Synthesis and Antifungal Activity Evaluation of 3-Hetaryl-2,5-dihydrofuran-2-ones. An Unusual Fragmentation of the Oxazole Ring via 2,3-Selenoxide Shift
J Kuneš, V Balšánek, M Pour… - … of Czechoslovak chemical …, 2001 - cccc.uochb.cas.cz
In continuing the studies on the synthesis and evaluation of antifungal activity of the
analogues of (-) incrustoporine, the replacement of the phenyl moiety at C3 of the furanone …
analogues of (-) incrustoporine, the replacement of the phenyl moiety at C3 of the furanone …
[HTML][HTML] Antifungal activity and mechanism of action of 2-chloro-N -phenylacetamide: a new molecule with activity against strains of Aspergillus flavus
ES Ferreira, LV Cordeiro, DDF Silva… - Anais da Academia …, 2021 - SciELO Brasil
Aspergillus genus causes many diseases, and the species Aspergillus flavus is highly
virulent. Treatment of aspergillosis involves azole derivatives such as voriconazole and …
virulent. Treatment of aspergillosis involves azole derivatives such as voriconazole and …
Antifungal 3, 5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives
P Šenel, L Tichotová, I Votruba, V Buchta… - Bioorganic & Medicinal …, 2010 - Elsevier
5-Acetoxymethyl-3-(4-bromophenyl)-2, 5-dihydrofuran-2-one previously described as highly
antifungally active was found to provide the corresponding 5-methylene derivative via an …
antifungally active was found to provide the corresponding 5-methylene derivative via an …
Augmenting the activity of antifungal agents against aspergilli using structural analogues of benzoic acid as chemosensitizing agents
JH Kim, BC Campbell, N Mahoney, KL Chan… - Fungal biology, 2010 - Elsevier
A number of benzoic acid analogues showed antifungal activity against strains of
Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human …
Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human …
Benzofurazan derivatives as antifungal agents against phytopathogenic fungi
L Wang, YY Zhang, L Wang, F Liu, LL Cao… - European Journal of …, 2014 - Elsevier
A series of benzofurazan derivatives were prepared and evaluated for their biological
activities against four important phytopathogenic fungi, namely, Rhizoctonia solani …
activities against four important phytopathogenic fungi, namely, Rhizoctonia solani …
[PDF][PDF] Inhibition of Aspergillus fumigatus Biofilm and Cytotoxicity Study of Natural Compound Cis-9-Hexadecenal.
Clinical limitations and drug-resistance are the basis of the search for new antifungal
therapeutics against biofilm forming pathogen Aspergillus fumigatus. Cis-9-hexadecenal is a …
therapeutics against biofilm forming pathogen Aspergillus fumigatus. Cis-9-hexadecenal is a …
[HTML][HTML] Novel Antifungal Agents and Their Activity against Aspergillus Species
R Vahedi-Shahandashti, C Lass-Flörl - Journal of Fungi, 2020 - mdpi.com
There is a need for new antifungal agents, mainly due to increased incidence of invasive
fungal infections (IFI), high frequency of associated morbidity and mortality and limitations of …
fungal infections (IFI), high frequency of associated morbidity and mortality and limitations of …
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