Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

Background: The quinoline moiety has been reported to be a privileged structure due to its
presence in many drugs. It appears in alkaloids and natural products such as quinine …

Nitrogen-rich heterocycles, particularly quinazolines and quinazolinones, represent a
unique class of diversified frameworks displaying a broad spectrum of biological functions …

Background: Plants produce a vast variety of specialized metabolites which can be a rich
source for lead compounds for the development of new drugs. Alkaloids are one the largest …

Covering: July 2002 to June 2003. Previous review: Nat. Prod. Rep., 2003, 20, 476 This
review covers the isolation, structure determination, synthesis and biological activity of …

The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …

Creating effective, ecologically friendly, and commercially viable synthetic routes is crucial in
the design and synthesis of organic substances. Quinazoline, a heterocyclic compound with …

Pyrroloiminoquinones are a group of cytotoxic alkaloids most commonly isolated from
marine sponges. Structurally, they are based on a tricyclic pyrrolo [4, 3, 2-de] quinoline core …

Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …