[HTML][HTML] Unraveling the biosynthesis of quinolizidine alkaloids using the genetic and chemical diversity of Mexican lupins

A Ramírez-Betancourt, AM Hernández-Sánchez… - Diversity, 2021 - mdpi.com
Quinolizidine alkaloids (QAs) are synthesized by the genus Lupinus as a defense against
herbivores. Synthesis of QAs in lupins is species-and organ-specific. Knowledge about their …

[PDF][PDF] Chemical and phytomedicinal investigations in Lunasia amara

AP Macabeo, A Aguinaldo - Pharmacognosy Reviews, 2008 - researchgate.net
Since the ancient period up to the current time, plants have been utilized by man as
medicinal agents on the basis of ethnomedical and folkloric beliefs. Later on, these …

Remarkably flexible quinazolinones—synthesis and biological applications

MM Reddy, A Sivaramakrishna - Journal of Heterocyclic …, 2020 - Wiley Online Library
Even though several quinazolinone derivatives have been synthesized, still there is a
constant demand for designing and synthesis of new quinazolinone derivatives by fine …

Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids

VK Nuthakki, R Mudududdla, SB Bharate - European Journal of Medicinal …, 2022 - Elsevier
Indoloquinoline (IQ) is an important class of naturally occurring antimalarial alkaloids, mainly
represented by cryptolepine, isocryptolepine, and neocryptolepine. The IQ structural …

Quinazolinones Isolated from Aspergillus sp., an Endophytic Fungus of Astragalus membranaceus

R Liu, H Li, J Yang, Z An - Chemistry of Natural Compounds, 2018 - Springer
Quinazolinones are an important class of fused heterocyclic scaffolds due to their significant
range of biological activities and their occurrence in approximately 200 naturally occurring …

[HTML][HTML] Recent advances and prospects in the organocatalytic synthesis of quinazolinones

B Borah, S Swain, M Patat, LR Chowhan - Frontiers in Chemistry, 2022 - frontiersin.org
Quinazolinone, a bicyclic compound comprises a pyrimidine ring fused at 4´ and 8´
positions with a benzene ring constitutes a substantial class of nitrogen-containing …

A Compilation of Synthetic Strategies to Access the Most Utilized Indoloquinoline Motifs

C Thongsornkleeb, J Tummatorn… - Chemistry–An Asian …, 2022 - Wiley Online Library
Indoloquinoline alkaloids constitute an important class of aromatic heterocycles consisting of
quinoline and indole fused together in various orientations. These compounds, both natural …

Total synthesis of makaluvamine A/D, damirone B, batzelline C, makaluvone, and isobatzelline C featuring one-pot benzyne-mediated cyclization–functionalization

T Oshiyama, T Satoh, K Okano, H Tokuyama - Tetrahedron, 2012 - Elsevier
Total synthesis of pyrroloquinoline alkaloids, such as makaluvamine A/D, damirone B,
batzelline C, makaluvone, and isobatzelline C, was achieved featuring a one-pot benzyne …

Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms

Y Li, G Wang, J Liu, L Ouyang - European Journal of Medicinal Chemistry, 2020 - Elsevier
Quinolizidine alkaloids, as essential active ingredients extracted from Sophora
alopecuroides Linn, have been well concerned in the past several decades owing to the …

Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: advances in synthesis and medicinal chemistry

MD Matveeva, R Purgatorio… - Future Medicinal …, 2019 - Future Science
Pyrrolo [2, 1-a] isoquinoline (PIq) is a nitrogen heterocyclic scaffold of diverse alkaloids
endowed with several biological activities, including antiretroviral and antitumor activities …