Total synthesis of makaluvamine A/D, damirone B, batzelline C, makaluvone, and isobatzelline C featuring one-pot benzyne-mediated cyclization–functionalization

T Oshiyama, T Satoh, K Okano, H Tokuyama - Tetrahedron, 2012 - Elsevier
Total synthesis of pyrroloquinoline alkaloids, such as makaluvamine A/D, damirone B,
batzelline C, makaluvone, and isobatzelline C, was achieved featuring a one-pot benzyne …

Pyrroloquinoline derivatives from a Tongan specimen of the marine sponge Strongylodesma tongaensis

T Taufa, RMA Gordon, MA Hashmi, K Hira, JH Miller… - Tetrahedron letters, 2019 - Elsevier
Pyrroloquinoline alkaloids are well known bioactive metabolites commonly found from
latrunculiid sponges. Two new pyrroloquinoline alkaloids, 6-bromodamirone B (1) and …

Metabolic engineering for the production of plant isoquinoline alkaloids

A Diamond, I Desgagné‐Penix - Plant biotechnology journal, 2016 - Wiley Online Library
Several plant isoquinoline alkaloids (PIA s) possess powerful pharmaceutical and
biotechnological properties. Thus, PIA metabolism and its fascinating molecules, including …

[PDF][PDF] A REVIEW ON INDOLO [2, 3-a] QUINOLIZIDINE: THE SYNTHETIC APPROACHES TO THE DEVELOPMENT OF BIOACTIVE INDOLO [2, 3-a] QUINOLIZIDINE …

S Sharma, Y Monga, A Gupta, S Singh - Heterocycles, 2023 - researchgate.net
Tetracyclic indolo [2, 3-a] quinolizidine motifs are an important class of molecules in
research and development due to their wide spectrum of biological activities, which include …

[HTML][HTML] Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis

XH Tian, LL Hong, WH Jiao, HW Lin - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2010 to 2021 Sesquiterpene quinone/quinols (SQs) are characterized by a C15-
sesquiterpenoid unit incorporating a C6-benzoquinone/quinol moiety. Numerous …

Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020)

AN Kim, A Ngamnithiporn, E Du, BM Stoltz - Chemical Reviews, 2023 - ACS Publications
The tetrahydroisoquinoline (THIQ) natural products constitute one of the largest families of
alkaloids and exhibit a wide range of structural diversity and biological activity. Ranging from …

Recent developments of quinoline derivatives and their potential biological activities

M Dib, H Ouchetto, K Ouchetto, A Hafid… - Current Organic …, 2021 - ingentaconnect.com
Heterocyclic compounds containing the quinoline ring play a significant role in organic
synthesis and therapeutic chemistry. Polyfunctionalized quinolines have attracted the …

Bisbenzylisoquinoline alkaloids

C Weber, T Opatz - The Alkaloids: Chemistry and Biology, 2019 - Elsevier
The present review covers the literature on bisbenzylisoquinoline alkaloids from 1999
through early 2018. About 500 natural products belong to this large alkaloid class, of which …

Stereoselective synthesis of fused-, spiro-and bridged heterocycles via cyclization of isoquinolinium salts: a recent update

S Das - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Isoquinoline and its derivatives are ubiquitous in natural alkaloids, synthetic materials and
pharmaceuticals with a broad spectrum of biological activities. In particular, isoquinolinium …

Synthetic routes to quinoline-based derivatives having potential anti-bacterial and anti-fungal properties

S Sharma, S Singh - Current Organic Chemistry, 2022 - ingentaconnect.com
Quinoline and its derivatives are part of several natural products. Many of them are active
pharmacophores and show enormous biological activities. Owing to their usefulness in drug …