Abstract Severe infections (SIs) in Intensive Care Units (ICUs) constitute difficult therapeutic
problems confronting clinicians who deal with severely ill patients. Some SIs are …

Indications for the use of antimicrobials in critically ill patients are similar to those for other
hospitalised patients. However, the selection of agents depends on the particular …

Every intensive care unit should have well-structured guidelines on the use of antimicrobial
agents to guarantee that patients requiring intensive care receive appropriate antimicrobials …

Abstract Although only 5–10% of all hospitalized patients are treated in ICUs, they account
for approximately 25% of all nosocomial infections, and the incidence of nosocomial …

Between 5 and 10% of patients admitted to acute care hospitals acquire one or more
infections, and the risks have steadily increased during recent decades. Three types of …

In the management of a patient with severe sepsis, it is important to suspect the infection
early, to collect samples immediately after diagnosis and to promptly initiate a broad …

Objectives: To prospectively assess the use of antibiotics in ICUs. Patients and methods: A
total of 979 critically ill patients over 14 years of age were recruited in 43 Italian ICUs. For …

Nosocomial infections (NIs) are among the most difficult problems confronting clinicians who
deal with severely ill patients. The incidence of these hospital-acquired infections varies with …

Antimicrobial resistance in microorganisms increased inexorably driven by antimicrobial
exposure in healthcare, agriculture, and the environment. Onward transmission is affected …

To the Editor—The journal recentiy published articles by Dellit et al. 1 and by Cook et al. 2
that strongly highlight the need for multidisciplinary approaches to antimicrobial therapy in …