Rationale and Objectives: There are limited data on, and controversies regarding gender
differences in the airway dimensions of smokers. Multi-detector CT (MDCT) images were …

Background The prevalence of chronic obstructive pulmonary disease (COPD) in women is
fast approaching that in men, and women experience greater symptom burden. Although …

Background In CT scans of smokers with COPD, the subsegmental airway wall area percent
(WA%) is greater and more strongly correlated with FEV 1% predicted than WA% obtained …

Background It is time-consuming to obtain the square root of airway wall area of the
hypothetical airway with an internal perimeter of 10 mm (√ Aaw at Pi10), a comparable …

Background The authors of previous reports have suggested that women are more
susceptible to cigarette smoke and to an airway-predominant COPD phenotype rather than …

PURPOSE: To design and validate a dedicated software tool to measure airway dimensions
on thin-section computed tomographic (CT) images and to use the tool to prospectively …

Background COPD is characterised by reduced airway lumen dimensions and fewer
peripheral airways. Most studies of airway properties sample airways based upon lumen …

Objective: It is not well known whether there is heterogeneity in the airway dimensions at
different anatomic locations in individual patients with COPD. The first objective was to …

Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
obstruction caused by emphysema or airway narrowing, or both. Recently airway …

Background Increased airway wall thickness (AWT) and parenchymal lung destruction
bothcontribute to airflow limitation. Advances in computed tomography (CT) post-processing …