[HTML][HTML] Distinguishing pain from nociception, salience, and arousal: how autonomic nervous system activity can improve neuroimaging tests of specificity

IS Lee, EA Necka, LY Atlas - Neuroimage, 2020 - Elsevier
Pain is a subjective, multidimensional experience that is distinct from nociception. A large
body of work has focused on whether pain processing is supported by specific, dedicated …

Spatial patterns of brain activity preferentially reflecting transient pain and stimulus intensity

M Liang, Q Su, A Mouraux, GD Iannetti - Cerebral Cortex, 2019 - academic.oup.com
How pain emerges in the human brain remains an unresolved question. Neuroimaging
studies have suggested that several brain areas subserve pain perception because their …

Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals

L Van Oudenhove, PA Kragel, P Dupont, HG Ly… - Nature …, 2020 - nature.com
Different pain types may be encoded in different brain circuits. Here, we examine similarities
and differences in brain processing of visceral and somatic pain. We analyze data from …

[HTML][HTML] Brain regions preferentially responding to transient and iso-intense painful or tactile stimuli

Q Su, W Qin, QQ Yang, CS Yu, TY Qian, A Mouraux… - NeuroImage, 2019 - Elsevier
How pain emerges from cortical activities remains an unresolved question in pain
neuroscience. A first step toward addressing this question consists in identifying brain …

Disentangling linear and nonlinear brain responses to evoked deep tissue pain

ML Loggia, RR Edwards, J Kim, MG Vangel, AD Wasan… - PAIN®, 2012 - Elsevier
Pain stimuli evoke widespread responses in the brain. However, our understanding of the
physiological significance underlying heterogeneous response within different pain …

Pain modalities in the body and brain: Current knowledge and future perspectives

Y Chae, HJ Park, IS Lee - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Abstract Development and validation of pain biomarkers has become a major issue in pain
research. Recent advances in multimodal data acquisition have allowed researchers to …

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis

A Xu, B Larsen, EB Baller, JC Scott, V Sharma… - … & biobehavioral reviews, 2020 - Elsevier
Characterizing a reliable, pain-related neural signature is critical for translational
applications. Many prior fMRI studies have examined acute nociceptive pain-related brain …

The search for pain biomarkers in the human brain

A Mouraux, GD Iannetti - Brain, 2018 - academic.oup.com
Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …

Neuroimaging-based evidence for sympathetic correlation between brain activity and peripheral vasomotion during pain anticipation

Z Xu, Z Soh, Y Kurota, Y Kimura, H Hirano… - Scientific Reports, 2024 - nature.com
Anticipation of pain engenders anxiety and fear, potentially shaping pain perception and
governing bodily responses such as peripheral vasomotion through the sympathetic …

Dissociation between individual differences in self-reported pain intensity and underlying fMRI brain activation

ME Hoeppli, H Nahman-Averbuch, WA Hinkle… - Nature …, 2022 - nature.com
Pain is an individual experience. Previous studies have highlighted changes in brain
activation and morphology associated with within-and interindividual pain perception. In this …