Pharmacogenetics factors influencing smoking cessation success; the importance of nicotine metabolism
YX Perez-Paramo, P Lazarus - Expert opinion on drug metabolism …, 2021 - Taylor & Francis
Introduction: Smoking remains a worldwide epidemic, and despite an increase in public
acceptance of the harms of tobacco use, it remains the leading cause of preventable death …
acceptance of the harms of tobacco use, it remains the leading cause of preventable death …
Smoking cessation treatment: pharmacogenetic assessment.
This review focuses on the current status and future directions of pharmacogenetics
research into responses to treatments for nicotine dependence and smoking cessation …
research into responses to treatments for nicotine dependence and smoking cessation …
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes
AB Gold, C Lerman - Human genetics, 2012 - Springer
Many smokers attempt to quit smoking but few are successful in the long term. The
heritability of nicotine addiction and smoking relapse have been documented, and research …
heritability of nicotine addiction and smoking relapse have been documented, and research …
Pharmacogenetics of smoking: how far to the clinic?
M Quaak, FJ van Schooten, CP van Schayck - Pharmacogenomics, 2014 - Taylor & Francis
Recent research strongly suggests that a specific genetic background influences
smokingbehavior. Twin-and adoption-studies have demonstrated that genetic factors …
smokingbehavior. Twin-and adoption-studies have demonstrated that genetic factors …
Pathways to precision medicine in smoking cessation treatments
Cigarette smoking is highly addictive and modern genetic research has identified robust
genetic influences on nicotine dependence. An important step in translating these genetic …
genetic influences on nicotine dependence. An important step in translating these genetic …
Drugs and genotypes: how pharmacogenetic information could improve smoking cessation treatment
AM Lee, RF Tyndale - Journal of Psychopharmacology, 2006 - journals.sagepub.com
Current smoking cessation treatments are not optimal as the long-term abstinence rates are
low. Nicotine replacement therapy and bupropion are the only pharmacotherapies widely …
low. Nicotine replacement therapy and bupropion are the only pharmacotherapies widely …
From genes to treatments: a systematic review of the pharmacogenetics in smoking cessation
NC Salloum, ELF Buchalter, S Chanani… - …, 2018 - Taylor & Francis
Smoking cessation treatment outcomes may be heavily influenced by genetic variations
among smokers. Therefore, identifying specific variants that affect response to different …
among smokers. Therefore, identifying specific variants that affect response to different …
Genetic influences on smoking: a brief review
N Al Koudsi, RF Tyndale - Therapeutic drug monitoring, 2005 - journals.lww.com
Smoking is a complex behavior influenced by environmental and genetic factors. A number
of twin studies demonstrate genetic influences on multiple aspects of smoking including …
of twin studies demonstrate genetic influences on multiple aspects of smoking including …
Pharmacogenetic optimization of smoking cessation treatment
MJ Chenoweth, RF Tyndale - Trends in pharmacological sciences, 2017 - cell.com
Worldwide, approximately one billion people smoke cigarettes. Cigarette smoking persists in
part because long-term smoking cessation rates are modest on existing treatments. Smoking …
part because long-term smoking cessation rates are modest on existing treatments. Smoking …
Genetics and smoking cessation: improving outcomes in smokers at risk
CE Lerman, RA Schnoll, MR Munafò - American journal of preventive …, 2007 - Elsevier
This article reviews evidence supporting the potential utility of a pharmacogenetic approach
to the treatment of nicotine dependence. There is substantial evidence that nicotine …
to the treatment of nicotine dependence. There is substantial evidence that nicotine …