We describe the management and follow-up of a 20-year-old male with acute myeloblastic
leukemia with translocation (8; 21)[t (8; 21)]. A quantitative polymerase chain reaction for t (8; …

The translocation t (8; 21) is one of the most common structural aberrations in acute myeloid
leukemia (AML). Excellent response rates and a better relapse-free survival have been …

Nine acute myelogenous leukemia (AML) patients with a translocation 8; 21, who were
treated at Keio University Hospital between 1983 and August 1990, were reviewed. All of …

Abstract A translocation (6; 11)(q26–27; q23) was detected in four male patients diagnosed
with acute T-cell lymphoblastic leukemia and acute myelomonocytic and monocytic …

Translocations involving the EVI1/MDS1 gene at 3q26 and the TEL gene at 12p13 are
comparatively common in acute leukemia, but a translocation between the two genes has …

Twenty-three patients with de novo acute myeloid leukemia (AML) and t (8; 21)(q22; q22),
including 2 children aged 7 and 14 and 21 adults aged 16 to 68 (median 29), were treated …

More than 50% of adult patients with acute myeloid leukemia (AML) carry chromosome
abnormalities, like t (8; 21)(q22; q22), t (15; 17), t (8; 21) inv (16) or t (16; 16). t (10; 17) …

Because an increasing number of chromosomal aberrations have been detected in the
patients with acute leukemia, cytogenetic findings have become more valuable in …

From 1981 to 1992 forty acute myelocytic leukemia patients with the 8; 21 translocation [t (8;
21) AML] were treated with intensive chemotherapy and radiotherapy. Their ages ranged …

We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …