An important virulence strategy evolved by bacterial pathogens to overcome host defenses
is the modulation of host cell death. Previous observations have indicated that Yersinia …

The virulence of the pathogenic Yersinia species depends on a plasmid‐encoded type III
secretion system (T3SS) that transfers six Yersinia outer protein (Yop) effector proteins into …

Pulmonary infection with the bacterium Yersinia pestis causes pneumonic plague, an often-
fatal disease for which no vaccine is presently available. Antibody-mediated humoral …

The human-pathogenic species of the Gram-negative genus Yersinia preferentially target
and inactivate cells of the innate immune defense, suggesting that this is a critical step by …

Yersinia pestis is one of the most virulent pathogens known. A major development of Y.
pestis, as compared to Y. pseudotuberculosis from which it recently derived, is its ability to …

ABSTRACT A hallmark of Yersinia pestis infection is a delayed inflammatory response early
in infection. In this study, we use an intradermal model of infection to study early innate …

Neutrophils are the primary immune cell recruited to the site of bacterial infection, where
they can rapidly deploy vesicles filled with various pro-inflammatory and anti-microbial …

Yersinia pestis, causative agent of plague, is one of the deadliest pathogens around globe.
Innate immune response is first line of host defense against pathogens. Here, we have …

Three bacterial species within the genus Yersinia are causative agents of human disease.
Yersinia pestis is transmitted by fleas or in aerosols, infects regional lymph nodes or lungs …

Plague is a zoonotic disease caused by Yersinia pestis, the etiological agent of pneumonic
and bubonic plague. Thirty-two individuals were vaccinated with Y. pestis EV line NIIEG and …