Turning Yersinia pathogenesis outside in: subversion of macrophage function by intracellular yersiniae

C Pujol, JB Bliska - Clinical immunology, 2005 - Elsevier
Three bacterial species within the genus Yersinia are causative agents of human disease.
Yersinia pestis is transmitted by fleas or in aerosols, infects regional lymph nodes or lungs …

The in vitro evaluation of anti-plague cellular immunity by quantitative analysis of IFN-γ synthesis and the appearance of activation molecules on the surface of T …

VV Firstova, EA Tyurin, TB Kravchenko… - Advances in Yersinia …, 2012 - Springer
Plague is a zoonotic disease caused by Yersinia pestis, the etiological agent of pneumonic
and bubonic plague. Thirty-two individuals were vaccinated with Y. pestis EV line NIIEG and …

Susceptibility to Yersinia pseudotuberculosis Infection is Linked to the Pattern of Macrophage Activation

A Tansini, BMM De Medeiros - Scandinavian journal of …, 2009 - Wiley Online Library
T helper 1 cells play a crucial role in the clearance of Yersinia pseudotuberculosis infection.
By producing cytokines and presenting antigens to T cells, activated macrophages can …

The pH 6 Antigen Is an Antiphagocytic Factor Produced by Yersinia pestis Independent of Yersinia Outer Proteins and Capsule Antigen

XZ Huang, LE Lindler - Infection and immunity, 2004 - Am Soc Microbiol
ABSTRACT The pH 6 antigen (pH 6 Ag; PsaA) of Yersinia pestis has been shown to be a
virulence factor. In this study, we set out to investigate the possible function of Y. pestis PsaA …

Reduced Apoptosis of Mouse Macrophages Induced by yscW Mutant of Yersinia pestis Results from the Reduced Secretion of YopJ and Relates to Caspase‐3 …

Y Bi, Z Du, H Yang, Z Guo, Y Tan… - … journal of immunology, 2009 - Wiley Online Library
The virulence of the pathogenic Yersinia species depends on a plasmid‐encoded type III
secretion system (T3SS) that injects six Yersinia outer protein (Yop) effector proteins into the …

Intraspecific Diversity of Yersinia pestis

AP Anisimov, LE Lindler, GB Pier - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Increased interest in the pathogenic potential of Yersinia pestis has emerged because of the
potential threats from bioterrorism. Pathogenic potential is based on genetic factors present …

Yersinia pestis and plague

RW Titball, J Hill, DG Lawton… - Biochemical Society …, 2003 - portlandpress.com
Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially
devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia …

Delineation and Analysis of Chromosomal Regions Specifying Yersinia pestis

A Derbise, V Chenal-Francisque, C Huon… - Infection and …, 2010 - Am Soc Microbiol
Yersinia pestis, the causative agent of plague, has recently diverged from the less virulent
enteropathogen Yersinia pseudotuberculosis. Its emergence has been characterized by …

Cellular Immune Response to Yersinia pestis Modulated by Product (s) from Thymus-Derived Lymphocytes

JF Wong, SS Elberg - Journal of Infectious Diseases, 1977 - academic.oup.com
Resistance to infection with Yersinia pestis was found to depend on whether the
macrophage can inactivate and withstand the cytotoxic effects of phagocytized Y. pestis …

Natural history of Yersinia pestis pneumonia in aerosol-challenged BALB/c mice

HS Heine, L Chuvala, R Riggins… - Antimicrobial agents …, 2013 - Am Soc Microbiol
After a relatively short untreated interval, pneumonic plague has a mortality approaching
100%. We employed a murine model of aerosol challenge with Yersinia pestis to investigate …