Within the vertebrate nervous system, the presence of many different lineages of neurons
and glia complicates the molecular characterization of single neuronal populations. In order …

During neocortical development, neurons undergo polarization, oriented migration, and
layer-type-specific differentiation. The transcriptional programs underlying these processes …

Pyramidal neurons of the neocortex can be subdivided into two major groups: deep-(DL)
and upper-layer (UL) neurons. Here we report that the expression of the AT-rich DNA …

Pyramidal neurons in the deep layers of the cerebral cortex can be classified into two major
classes: callosal projection neurons and long-range subcortical neurons. We and others …

Expression of the transcriptional repressor Zbtb20 is confined to the hippocampal
primordium of the developing dorsal midline cortex in mice. Here, we show that …

Generation of distinct cortical projection neuron subtypes during development relies in part
on repression of alternative neuron identities. It was reported that the special AT-rich …

Excitatory cortical neurons project to various subcortical and intracortical regions, and
exhibit diversity in their axonal connections. Although this diversity may develop from …

The generation and differentiation of cortical projection neurons are extensively regulated by
interactive programs of transcriptional factors. Here, we report the cooperative functions of …

Striatal medium spiny neurons (MSN) are critically involved in motor control, and their
degeneration is a principal component of Huntington's disease. We find that the transcription …

Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in
progenitor cells and then, implemented in postmitotic neurons. Here, we report that Tbr1, a …