A derepression mode of cell-fate specification involving the transcriptional repressors Tbr1,
Fezf2, Satb2, and Ctip2 operates in neocortical projection neurons to specify six layer …

In the nervous system, BCL11B is crucial for the development of deep layer corticospinal
projection neurons and striatal medium spiny neurons and is often used as a marker for the …

The chromatin-remodeling protein Satb2 plays a role in the generation of distinct subtypes of
neocortical pyramidal neurons. Previous studies have shown that Satb2 is required for …

Cerebral cortical development is controlled by key transcription factors that specify the
neuronal identities in the different layers. The mechanisms controlling their expression in …

The precise stereotypic projections of pyramidal neurons within the six-layered cortex of
mammals are key in allowing this structure to attain its high level of function. Recent studies …

The mammalian neocortex is a highly organized six-layered structure with four major cortical
neuron subtypes: corticothalamic projection neurons (CThPNs), subcerebral projection …

An important feature of the cerebral cortex is its layered organization, which is modulated in
an area-specific manner. We found that the transcription factor AP2γ regulates laminar fate …

Hippocampal pyramidal neurons are important for encoding and retrieval of spatial maps
and episodic memories. While previous work has shown that Zbtb20 is a cell fate …

The development of the dentate gyrus is characterized by distinct phases establishing a
durable stem‐cell pool required for postnatal and adult neurogenesis. Here, we report that …

The transcription factors Satb2 (special AT‐rich sequence binding protein 2) and Ctip2
(COUP‐TF interacting protein 2) have been shown to be required for callosal and …