Summary T-brain gene-2 (Tbr2) is specifically expressed in the intermediate (basal)
progenitor cells (IPCs) of the developing cerebral cortex; however, its function in this …

Neuronal phenotypes are controlled by terminal selector transcription factors in
invertebrates, but only a few examples of such regulators have been provided in vertebrates …

Highly ordered brain architectures in vertebrates consist of multiple neuron subtypes with
specific neuronal connections. However, the origin of and evolutionary changes in neuron …

Cells of the subplate (SP) and deep cortical plate (CP) are among the pioneer neurons of
the developing cerebral cortex; an important group of early born cells that impact cortical …

Intermediate progenitors (IPs) amplify the production of pyramidal neurons, but their role in
selective genesis of cortical layers or neuronal subtypes remains unclear. Using genetic …

The mammalian telencephalon contains distinct GABAergic projection neuron and
interneuron types, originating in the germinal zone of the embryonic basal ganglia. How …

Cell–cell interactions are primarily mediated by secreted and transmembrane proteins which
play essential roles in the neuronal circuit formation. However, molecular mechanisms …

Background During corticogenesis, genetic programs encoded in progenitor cells at different
developmental stages and inherited in postmitotic neurons specify distinct layer and area …

The retrosplenial cortex (Rsp) is a transitional cortex located between the neocortex and
archicortex, but the molecular mechanism specifying Rsp from the archicortex remains …

Little is known about how, during its formidable expansion in development and evolution,
the cerebral cortex is able to maintain the correct balance between excitatory and inhibitory …