The organization, function and evolution of the brain depends centrally on the precise
development of a wide diversity of distinct neuronal subtypes. Furthermore, given the …

C-terminal binding proteins (CtBPs) are well-characterized nuclear transcriptional co-
regulators. In addition, cytoplasmic functions were discovered for these ubiquitously …

The current model, based on rodent data, proposes that thalamocortical afferents (TCA)
innervate the subplate towards the end of cortical neurogenesis. This implies that the …

Several transcription factors are essential determinants of a cortical projection neuron
identity, but their mode of action (instructive versus permissive) and downstream genetic …

The PC3/Tis21/Btg2 and Btg1 genes are transcriptional cofactors belonging to the Btg/Tob
family, which regulate the development of several cell types, including neural precursors …

Developmental neuron death plays a pivotal role in refining organization and wiring during
neocortex formation. Aberrant regulation of this process results in neurodevelopmental …

In developing cerebral cortex, intermediate progenitors (IP s) are transit amplifying cells that
specifically express Tbr2 (gene: Eomes), a T‐box transcription factor. IP s are derived from …

Molecular controls over the development of the exceptional neuronal subtype diversity of the
cerebral cortex are now beginning to be identified. The initial subtype fate decision early in …

Chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2
(CTIP2), also known as Bcl11b, is a transcriptional repressor that functions by direct …

The rodent somatosensory cortex includes well-defined examples of cortical columns—the
barrel columns—that extend throughout the cortical depth and are defined by discrete …