In the developing cerebral cortex, cell-extrinsic and cell-intrinsic signals govern the
establishment of neuron subtype-specific identity. Here we show that, within the niche of the …

BMPs have been proposed to pattern the medial-lateral axis of the telencephalon in a
concentration-dependent manner, thus helping to subdivide the embryonic telencephalon …

Abstract Bcl11A/Evi9/CTIP1, a Kruppel‐like zinc finger gene, plays an important role in B‐
cell development. In addition to expression in B lymphocytes, Bcl11A/Evi9/CTIP1 is also …

Cerebral cortex expansion is a hallmark of mammalian brain evolution; yet, how increased
neurogenesis is coordinated with structural and functional development remains largely …

The thalamus acts as a central integrator for processing and relaying sensory and motor
information to and from the cerebral cortex, and the habenula plays pivotal roles in emotive …

Regulation of region-specific neuronal differentiation and migration in the embryonic
forebrain is a complex mechanism that involves a variety of transcription factors such as the …

Mutations in each of the transcriptional co-activator genes-CBP, p300, Cited2, Cart1 and
Carm1-result in neural tube defects in mice. The present study thus furnishes a complete …

The thalamus receives input from 3 distinct cortical layers, but input from only 2 of these has
been well characterized. We therefore investigated whether the third input, derived from …

The development of the cerebral cortex depends on numerous parameters, including
extracellular cues and microenvironmental factors that also affect gene expression. C …

The mature cerebral cortex contains a staggering variety of projection neuron subtypes, and
a number of complementary studies have recently begun to define their identity and …