Tumor repressive functions of estrogen receptor β in SW480 colon cancer cells

J Hartman, K Edvardsson, K Lindberg, C Zhao… - Cancer research, 2009 - AACR
Estrogen receptor β (ERβ) is the predominant ER in the colorectal epithelium. Compared
with normal colon tissue, ERβ expression is reduced in colorectal cancer. Our hypothesis is …

[HTML][HTML] ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components

V Martineti, L Picariello, I Tognarini… - Endocrine-related …, 2005 - erc.bioscientifica.com
Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …

Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells

K Edvardsson, A Ström, P Jonsson… - Molecular …, 2011 - academic.oup.com
Several studies suggest estrogen to be protective against the development of colon cancer.
Estrogen receptor β (ERβ) is the predominant estrogen receptor expressed in colorectal …

Estrogen receptor β inhibits 17β-estradiol-stimulated proliferation of the breast cancer cell line T47D

A Ström, J Hartman, JS Foster, S Kietz… - Proceedings of the …, 2004 - National Acad Sciences
Estrogen receptor (ER) β counteracts the activity of ERα in many systems. In agreement with
this, we show in this study that induced expression of ERβ in the breast cancer cell line …

[HTML][HTML] Expression of estrogen receptor β in human colorectal cancer

LQ Xie, JP Yu, HS Luo - World Journal of Gastroenterology, 2004 - ncbi.nlm.nih.gov
AIM: To determine the expression of estrogen receptor (ER) β in Chinese colorectal
carcinoma (CRC) patients. METHODS: ERβ expression in CRC was investigated by …

Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation

PA Konstantinopoulos, A Kominea, G Vandoros… - European journal of …, 2003 - Elsevier
Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer

M Campbell-Thompson, IJ Lynch, B Bhardwaj - Cancer research, 2001 - AACR
Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …

Selective loss of estrogen receptor β in malignant human colon

EF Foley, AA Jazaeri, MA Shupnik, O Jazaeri, LW Rice - Cancer Research, 2000 - AACR
Epidemiological data suggest a protective effect for estrogen replacement therapy on colon
cancer. The estrogen receptor (ER) is required for the action of estrogen. The ER-β isoform …

Implications of estrogen and its receptors in colorectal carcinoma

PK Das, J Saha, S Pillai, AKY Lam, V Gopalan… - Cancer …, 2023 - Wiley Online Library
Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …

Estrogen receptor β is expressed in human colorectal adenocarcinoma

D Witte, M Chirala, A Younes, Y Li, M Younes - Human pathology, 2001 - Elsevier
Estrogen receptor β (ER-β) has recently been detected in a human colon cancer cell line.
The aim of this work was to determine whether ER-β is expressed in human colorectal …