Objectives: The objectives of this article are to review the prevalence, natural history,
pathophysiology, and treatment of comorbid bipolar disorder with alcoholism and other …

The aim of this paper is to provide a systematic review of the literature examining the
epidemiology, outcome, and treatment of patients with bipolar disorder and co-occurring …

Alcohol and drug abuse occur frequently in individuals with bipolar disorder, but clinicians
may often feel ill-prepared to identify such multi-diagnosis syndromes, to contextualize drug …

Comorbidity rates in Bipolar disorder rank highest among major mental disorders, especially
comorbid substance use. Besides cannabis, alcohol is the most frequent substance of abuse …

Classic Kraepelian observations and contemporary epidemiological studies have noted a
high prevalence rate between bipolar disorder and alcoholism. The extent to which these …

Substance use disorders are overrepresented in individuals with bipolar and bipolar
spectrum disorders. Although awareness of this phenomenon has increased over the past …

Bipolar disorder and alcohol use disorder represent a significant comorbid population,
which is significantly worse than either diagnosis alone in presentation, duration, co …

Population-based studies have documented that among all patients with major psychiatric
disorders, those with bipolar disorder have the highest prevalence of comorbid substance …

Bipolar disorder is a severe and often chronic disorder with lifetime prevalence rates of
bipolar spectrum disorders of up to 6.5% in the general population. Patients with bipolar …

Background: High rates of substance abuse have been reported in the general population,
with males more often affected than females. Although high rates of substance abuse have …