Aims Several studies have indicated that insulin that is used in reducing blood glucose is
also affective on wound healing by various mechanisms. To understand the outcomes of …

This study investigates if different diabetic treatment regimens affect diabetic foot ulcer
healing. From January 2013 to December 2014, 107 diabetic foot ulcers in 85 patients were …

Background: Growth-promoting polypeptides, including insulin-like growth factor-I (IGF-I),
orchestrate different biochemical events that culminate in the restoration of functional …

Wound-healing disorders are major complications of diabetes mellitus. Here, we
investigated insulin-mediated signaling in nonwounded skin and in cutaneous tissue …

In the present study wound healing was examined in normal C57B1/6 male mice, diabetic
mice, non-treated; and in diabetic mice treated with insulin. Small dermal wounds were …

Impaired wound healing frequently occurs in patients with diabetes. Interleukin (IL)-8
production by keratinocyte is responsible for recruiting neutrophils during healing. Intense …

Impaired wound healing is an enigmatic and debilitating complication of diabetes. A
consensus as to the pathogenesis of this disorder has yet to emerge. Recent concepts …

Background. Insulin is proposed as a therapy for suppressing muscle wasting after burn
trauma although the long-term effects of this therapy on wound healing are not yet known …

Impaired wound healing of skin is one of the most serious complications of diabetes.
However, the pathogenesis of this process is not known, and it is unclear whether impaired …

Diabetes is associated with persistent inflammation and defective tissue repair responses.
The hypothesis of this study was that interleukin (IL)-1β is part of a proinflammatory positive …