Stx-phages: drivers and mediators of the evolution of STEC and STEC-like pathogens

HE Allison - 2007 - Future Medicine
Bacteriophages, also known as phages, are viruses that infect bacteria. Until recently they
have been ignored by most of the scientific community, but their impact upon our world is …

Shiga toxin-producing Escherichia coli strains from cattle as a source of the Stx2a bacteriophages present in enteroaggregative Escherichia coli O104: H4 strains

L Beutin, JA Hammerl, J Reetz, E Strauch - International Journal of Medical …, 2013 - Elsevier
Enteroaggregative, Shiga toxin-producing E. coli (EAEC-STEC) O104: H4 strains are
emerging pathogens causing life threatening diseases in humans. EAEC-STEC O104: H4 …

Insights into the genome architecture and evolution of Shiga toxin encoding bacteriophages of Escherichia coli

G Pinto, M Sampaio, O Dias, C Almeida, J Azeredo… - BMC genomics, 2021 - Springer
Background A total of 179 Shiga toxin-producing Escherichia coli (STEC) complete
genomes were analyzed in terms of serotypes, prophage coding regions, and stx gene …

Bacteriophages of Shiga Toxin-Producing Escherichia coli and Their Contribution to Pathogenicity

L Rodríguez-Rubio, N Haarmann, M Schwidder… - Pathogens, 2021 - mdpi.com
Shiga toxins (Stx) of Shiga toxin-producing Escherichia coli (STEC) are generally encoded
in the genome of lambdoid bacteriophages, which spend the most time of their life cycle …

Isogenic lysogens of diverse Shiga toxin 2-encoding bacteriophages produce markedly different amounts of Shiga toxin

PL Wagner, DWK Acheson, MK Waldor - Infection and immunity, 1999 - Am Soc Microbiol
We produced isogenic Escherichia coli K-12 lysogens of seven different Shiga toxin 2 (Stx2)-
encoding bacteriophages derived from clinical Shiga toxin-producing E. coli (STEC) isolates …

Bacteriophage 2851 Is a Prototype Phage for Dissemination of the Shiga Toxin Variant Gene 2c in Escherichia coli O157:H7

E Strauch, JA Hammerl, A Konietzny… - Infection and …, 2008 - Am Soc Microbiol
The production of Shiga toxin (Stx)(verocytotoxin) is a major virulence factor of Escherichia
coli O157: H7 strains (Shiga toxin-producing E. coli [STEC] O157). Two types of Shiga …

One of Two Copies of the Gene for the Activatable Shiga Toxin Type 2d in Escherichia coli O91:H21 Strain B2F1 Is Associated with an Inducible Bacteriophage

LD Teel, AR Melton-Celsa, CK Schmitt… - Infection and …, 2002 - Am Soc Microbiol
Shiga toxin (Stx) types 1 and 2 are encoded within intact or defective temperate
bacteriophages in Stx-producing Escherichia coli (STEC), and expression of these toxins is …

Shiga toxin 2 is specifically released from bacterial cells by two different mechanisms

T Shimizu, Y Ohta, M Noda - Infection and immunity, 2009 - Am Soc Microbiol
ABSTRACT Shiga toxin 1 (Stx1) is located in the periplasmic fraction, while Stx2 is found in
the extracellular fraction, suggesting that enterohemorrhagic Escherichia coli (EHEC) …

Prevalence of Stx Phages in Environments of a Pig Farm and Lysogenic Infection of the Field E. coli O157 Isolates with a Recombinant Converting Phage

Y Yan, Y Shi, D Cao, X Meng, L Xia, J Sun - Current microbiology, 2011 - Springer
The prevalence and nature of Shiga toxin (Stx)-producing Escherichia coli (STEC) and Stx
phage were investigated in 720 swine fecal samples randomly collected from a commercial …

Distinctiveness of the genomic sequence of Shiga toxin 2-converting phage isolated from Escherichia coli O157: H7 Okayama strain as compared to other Shiga toxin …

T Sato, T Shimizu, M Watarai, M Kobayashi, S Kano… - Gene, 2003 - Elsevier
Shiga toxin 2-converting phage was isolated from Escherichia coli O157: H7 associated with
an outbreak that occurred in Okayama, Japan in 1996 (M. Watarai, T. Sato, M. Kobayashi, T …