MicroRNA-532-5p-programmed cell death protein 4 (PDCD4) axis regulates angiotensin II-induced human umbilical vein endothelial cell apoptosis and proliferation

Y Wang, C Gao, K Zhou, W Liu, Y Zhang, Y Zhao - Microvascular Research, 2021 - Elsevier
Background This study was carried out to investigate the effect of microRNA miR-532-5p on
the proliferation of hypertension endothelial cells. Methods Angiotensin II (Ang II)-treated …

Inhibition of circ_0000231 suppresses oxidized low density lipoprotein-induced apoptosis, autophagy and inflammation in human umbilical vein endothelial cells by …

H Lin, D Gao, S Wang, Z Wang, H Guan… - Clinical …, 2023 - content.iospress.com
Background: Circular RNAs (circRNAs) are the emerging informative RNAs, involved in
cardiovascular diseases including atherosclerosis (AS). Endothelial injury is the initial …

Effects of microRNA-499 on the inflammatory damage of endothelial cells during coronary artery disease via the targeting of PDCD4 through the NF-Κβ/TNF-α …

Z Yu-Hong - Cellular Physiology and Biochemistry, 2018 - search.proquest.com
Background/Aims: This study aimed to analyze the impact of microRNA-499 (miR-499) on
the inflammatory damage of endothelial cells during coronary artery disease (CAD) via the …

MicroRNA-126-5p inhibits apoptosis of endothelial cell in vascular arterial walls via NF‑κB/PI3K/AKT/mTOR signaling pathway in atherosclerosis

W Jia, J Liu, X Tian, P Jiang, Z Cheng… - Journal of Molecular …, 2022 - Springer
Atherosclerosis is considered as a chronic inflammatory disease. MicroRNA-126-5p (miR-
126-5p) may be pathophysiological relevant with the apoptotic processes in the endothelial …

An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease

X Liu, Y Cheng, J Yang, TJ Krall… - American Journal of …, 2010 - journals.physiology.org
It is well established that vascular smooth muscle cell (VSMC) apoptosis and proliferation
are critical cellular events in a variety of human vascular diseases. However, the molecular …

MicroRNA-384-mediated Herpud1 upregulation promotes angiotensin II-induced endothelial cell apoptosis

H Lin, S Pan, L Meng, C Zhou, C Jiang, Z Ji… - Biochemical and …, 2017 - Elsevier
Abstract Background Angiotensin II (Ang II)-induced damage to endothelial cells (ECs) plays
a crucial role in the pathogenesis of atherosclerosis. This study aimed to investigate the role …

[HTML][HTML] miRNA-9 inhibits apoptosis and promotes proliferation in angiotensin II-induced human umbilical vein endothelial cells by targeting MDGA2

K Tan, Y Ge, J Tian, S Li, Z Lian - Reviews in Cardiovascular Medicine, 2019 - imrpress.com
Hypertension is a universal risk factor for a variety of cardiovascular diseases. Investigation
of the mechanism for hypertension will benefit around 40% of the world's adult population …

Programmed cell death 6 (PDCD6) inhibits angiogenesis through PI3K/mTOR/p70S6K pathway by interacting of VEGFR-2

SB Rho, YJ Song, MC Lim, SH Lee, BR Kim, SY Park - Cellular signalling, 2012 - Elsevier
Programmed cell death 6 (PDCD6) was originally found as a pro-apoptotic protein, but its
molecular mechanism is not well understood. In this study, we have attempted to investigate …

[HTML][HTML] Effect of miR‑144‑5p on the proliferation, migration, invasion and apoptosis of human umbilical vein endothelial cells by targeting RICTOR and its related …

W Fu, Z Liu, J Zhang, Y Shi… - Experimental and …, 2020 - spandidos-publications.com
The purpose of the present study was to investigate the effect of microRNA (miR)‑144‑5p on
human umbilical vein endothelial cells (HUVECs) to explore the role of miR‑144‑5p in …

miR‐208 inhibits myocardial tissues apoptosis in mice with acute myocardial infarction by targeting inhibition of PDCD4

Q Wang, H Zhou, X Zhu, F Jiang, Q Yu… - … of Biochemical and …, 2022 - Wiley Online Library
This article aimed to investigate the role of miR‐208 in the apoptosis of myocardial tissues in
acute myocardial infarction (AMI) mice. The AMI mouse model was constructed. Then, miR …