Accumulating evidence has shown that tauroursodeoxycholic acid (TUDCA) is
neuroprotective in different animal models of neurological diseases. However, whether …

Depression is a mental disease that causes severe economic and social burdens. The
mechanism for the onset of depression remains largely unknown. Recently, more and more …

Neuroinflammation plays an important role in the pathophysiology of Alzheimer's disease
(AD) and memory impairment. Herein, we evaluated the neuroprotective effects of 6-ethyl-23 …

Alzheimer's disease (AD) is a neurodegenerative disease that affects cognition and
behavior. The neuroinflammatory response in the brain is an important pathological …

Background: Carvacrol is a natural phenolic monoterpene with anti-inflammatory and
antioxidant bioactivities. Neuroinflammatory and oxidative stress responses play a crucial …

Neuroinflammation is a predisposing factor for several neurodegenerative diseases. The
purpose of this study was to evaluate the protective effect of madecassoside (MA) in …

Background Bile acids are steroid acids found predominantly in the bile of mammals. The
bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in …

Background Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which
has been demonstrated to have neuroprotective effects in different neurological disease …

The bile acid conjugate tauroursodeoxycholic acid (TUDCA) is a neuroprotective agent in
various animal models of neuropathologies. We have previously shown the anti …

Evidence indicates that systemic administration of lipopolysaccharide (LPS) induces brain
inflammation, ultimately resulting in cognitive deficits. Ursolic acid (UA), a plant-derived …