Single inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind …
D Singh, A Papi, M Corradi, I Pavlišová, I Montagna… - The Lancet, 2016 - thelancet.com
Background Few data are available for the efficacy of" triple therapy" with two long-acting
bronchodilators and an inhaled corticosteroid in chronic obstructive pulmonary disease …
bronchodilators and an inhaled corticosteroid in chronic obstructive pulmonary disease …
Triple therapy for COPD: a crude analysis from a systematic review of the evidence
JL Lopez-Campos… - Therapeutic …, 2019 - journals.sagepub.com
We systematically reviewed the current knowledge on fixed-dose triple therapies for the
treatment of chronic obstructive pulmonary disease (COPD), with a specific focus on its …
treatment of chronic obstructive pulmonary disease (COPD), with a specific focus on its …
Future concepts in bronchodilation for COPD: dual-versus monotherapy
D Singh, JF Donohue, IH Boucot… - European …, 2021 - Eur Respiratory Soc
Most patients with COPD are recommended to initiate maintenance therapy with a single
long-acting bronchodilator, such as a long-acting muscarinic antagonist or long-acting β2 …
long-acting bronchodilator, such as a long-acting muscarinic antagonist or long-acting β2 …
Impact of baseline COPD symptom severity on the benefit from dual versus mono-bronchodilators: an analysis of the EMAX randomised controlled trial
CF Vogelmeier, EM Kerwin… - Therapeutic …, 2020 - journals.sagepub.com
Rationale: Symptom relief is a key treatment goal in patients with chronic obstructive
pulmonary disease (COPD). However, there are limited data available on the response to …
pulmonary disease (COPD). However, there are limited data available on the response to …
Patient-reported outcomes of dual bronchodilator fixed-dose combination versus bronchodilator monotherapy in individuals with COPD
C Strange, V Walker, M DePietro, J Tong… - … Journal of Chronic …, 2019 - Taylor & Francis
Background: This study compared real-world patient-reported outcomes (PROs) measured
by the Clinical COPD Questionnaire (CCQ), the London Chest Activities of Daily Living …
by the Clinical COPD Questionnaire (CCQ), the London Chest Activities of Daily Living …
Canadian Thoracic Society Clinical Practice Guideline on pharmacotherapy in patients with COPD–2019 update of evidence
In this guideline update, we highlight important and new findings related to pharmacological
therapy of chronic obstructive pulmonary disease (COPD) that should change clinical …
therapy of chronic obstructive pulmonary disease (COPD) that should change clinical …
[HTML][HTML] Once-daily single-inhaler triple versus dual therapy in patients with COPD
DA Lipson, F Barnhart, N Brealey… - … England Journal of …, 2018 - Mass Medical Soc
Background The benefits of triple therapy for chronic obstructive pulmonary disease (COPD)
with an inhaled glucocorticoid, a long-acting muscarinic antagonist (LAMA), and a long …
with an inhaled glucocorticoid, a long-acting muscarinic antagonist (LAMA), and a long …
[HTML][HTML] Comparisons of exacerbations and mortality among regular inhaled therapies for patients with stable chronic obstructive pulmonary disease: systematic …
Background Although exacerbation and mortality are the most important clinical outcomes of
stable chronic obstructive pulmonary disease (COPD), the drug classes that are the most …
stable chronic obstructive pulmonary disease (COPD), the drug classes that are the most …
[HTML][HTML] Trends and characteristics of global initiative for chronic obstructive lung disease guidelines-discordant prescribing of triple therapy among patients with …
SP Bhatt, C Blauer-Peterson, EK Buysman… - … Diseases: Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Triple therapy (long-acting muscarinic antagonist [LAMA] plus long-acting
beta2-agonist [LABA] plus inhaled corticosteroid [ICS]) is recommended by the Global …
beta2-agonist [LABA] plus inhaled corticosteroid [ICS]) is recommended by the Global …
Real-world outcomes in patients with chronic obstructive pulmonary disease initiating long-acting mono bronchodilator therapy
LGS Bengtson, M DePietro… - Therapeutic …, 2018 - journals.sagepub.com
Background: Randomized clinical trials have shown long-acting mono bronchodilator
therapy to be efficacious in improving lung function and dyspnea, while reducing …
therapy to be efficacious in improving lung function and dyspnea, while reducing …