Dual bronchodilation in COPD: lung function and patient-reported outcomes–a review

D Price, A Østrem, M Thomas… - International journal of …, 2016 - Taylor & Francis
Several fixed-dose combinations (FDCs) of long-acting bronchodilators (a long-acting
muscarinic antagonist [LAMA] plus a long-acting β2-agonist [LABA]) are available for the …

Combined corticosteroid and long‐acting beta2‐agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease

LJ Nannini, P Poole, SJ Milan… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Both long‐acting beta 2‐agonists and inhaled corticosteroids have been
recommended in guidelines for the treatment of chronic obstructive pulmonary disease …

FULFIL trial: once-daily triple therapy for patients with chronic obstructive pulmonary disease

DA Lipson, H Barnacle, R Birk, N Brealey… - American journal of …, 2017 - atsjournals.org
Rationale: Randomized data comparing triple therapy with dual inhaled corticosteroid
(ICS)/long-acting β2-agonist (LABA) therapy in patients with chronic obstructive pulmonary …

Optimum bronchodilator combinations in chronic obstructive pulmonary disease: what is the current evidence?

MC Miles, JF Donohue, JA Ohar - Drugs, 2012 - Springer
Chronic obstructive pulmonary disease (COPD) is a respiratory syndrome affecting more
than 80 million people worldwide and is estimated to become the third-leading cause of …

Initiation of triple therapy with multiple inhalers in chronic obstructive pulmonary disease: an analysis of treatment patterns from a US retrospective database study

DC Lane, S Stemkowski, RH Stanford, Z Tao - Journal of Managed Care & …, 2018 - jmcp.org
BACKGROUND: Evidence suggests that real-world treatment patterns of chronic obstructive
pulmonary disease (COPD) do not always follow evidence-based treatment …

Current appraisal of single inhaler triple therapy in COPD

B Lipworth, CRW Kuo, S Jabbal - International Journal of Chronic …, 2018 - Taylor & Francis
A single inhaler containing inhaled corticosteroid (ICS)/long-acting beta-agonist (LABA)/long-
acting muscarinic antagonist (LAMA) is a more convenient way of delivering triple therapy in …

Triple therapy in COPD: time for adaptive selection trials

S Suissa - COPD: Journal of Chronic Obstructive Pulmonary …, 2021 - Taylor & Francis
Recent trials reported significant reductions in all-cause mortality with single-inhaler triple
therapy for chronic obstructive pulmonary disease (COPD). However, reviews of these trials …

Inhaled triple therapy in individuals with Chronic Obstructive Pulmonary Disease and indications of pulmonary rehabilitation

M Vitacca, M Paneroni, A Spanevello… - European Journal of …, 2022 - ejinme.com
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease,
characterized by persistent and progressive airflow limitation, worsening reduced exercise …

[HTML][HTML] Optimal treatment sequence in COPD: Can a consensus be found?

J Ferreira, M Drummond, N Pires, G Reis… - Revista Portuguesa de …, 2016 - Elsevier
There is currently no consensus on the treatment sequence in chronic obstructive pulmonary
disease (COPD), although it is recognized that early diagnosis is of paramount importance …

Long-acting muscarinic antagonist versus inhaled corticosteroid when added to long-acting β-agonist for COPD: a meta-analysis

Y Oba, AV Chandran… - COPD: Journal of Chronic …, 2016 - Taylor & Francis
The purpose of this study was to systematically review the efficacy and safety of long-acting
β-agonist/long-acting muscarinic antagonist (LABA/LAMA) and LABA/inhaled corticosteroid …