Chronic obstructive pulmonary disease (COPD) is a complex disease which consists in the
reduction of the airflow and leads to the disruption of the pulmonary tissue due to a chronic …

Abstract Background In some RCTs comparing triple therapy with dual therapy in COPD,
there might be a bias resulting from the use of multiple inhaler devices. This meta-analysis …

Background Long-acting beta-agonists and inhaled corticosteroids have both been
recommended in guidelines for the treatment of chronic obstructive pulmonary disease …

Purpose Inappropriate use of an inhaled corticosteroid (ICS) for COPD has clinical and
economic disadvantages. This retrospective analysis of The UK Health Improvement …

Current evidence supports the recommendation of the Global Initiative for Chronic
Obstructive Lung Disease guidelines of at least one of the two classes of long-acting inhaled …

Patients with symptomatic advanced chronic obstructive pulmonary disease (COPD) who
experience recurrent exacerbations are particularly at risk of poor outcomes and present a …

Objective: To review clinical data on the use of long-acting bronchodilator agents as
monotherapy and in combination for the treatment of moderate-to-severe chronic obstructive …

The goals of COPD therapy are to prevent and control symptoms, reduce the frequency and
severity of exacerbations, and improve exercise tolerance. The triple combination therapy of …

COPD is a complex, heterogeneous condition. Even in the early clinical stages, COPD
carries a significant burden, with breathlessness frequently leading to a reduction in …

The cardiovascular risk of concurrently using long-acting β2-agonists (LABAs) and
anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative …