The role of mesenchymal stem cells in the functional improvement of chronic renal failure

S Choi, M Park, J Kim, S Hwang, S Park… - Stem cells and …, 2009 - liebertpub.com
The most commonly used therapeutic targets in nephrology are the reduction of injury, the
delay of progression, or renal replacement therapy. Many animal and human studies …

Mesenchymal stem cells in kidney repair

M Morigi, C Rota, G Remuzzi - Mesenchymal Stem Cells: Methods and …, 2016 - Springer
Every year 13.3 million people suffer acute kidney injury (AKI), which is associated with a
high risk of death or development of long-term chronic kidney disease (CKD) in a substantial …

Therapeutic applications of mesenchymal stem cells to repair kidney injury

H Asanuma, DR Meldrum, KK Meldrum - The Journal of urology, 2010 - Elsevier
PURPOSE: The potential use of stem cells for acute and chronic renal injury is under
intensive investigation. We summarized the current literature on the potential therapeutic …

Rationale of mesenchymal stem cell therapy in kidney injury

SV Fleig, BD Humphreys - Nephron Clinical Practice, 2014 - karger.com
Hundreds of clinical trials are currently investigating the potential for mesenchymal stem
cells (MSC) to treat human disease, including kidney disease. There is tremendous …

Mesenchymal stem cell treatment for chronic renal failure

A Eirin, LO Lerman - Stem cell research & therapy, 2014 - Springer
Chronic renal failure is an important clinical problem with significant socioeconomic impact
worldwide. Despite advances in renal replacement therapies and organ transplantation …

Repeated administration of bone marrow-derived mesenchymal stem cells improved the protective effects on a remnant kidney model

SR Lee, SH Lee, JY Moon, JY Park, D Lee, SJ Lim… - Renal failure, 2010 - Taylor & Francis
Mesenchymal stem cell (MSC) has been implied to have the therapeutic potential on chronic
kidney disease (CKD). However, the underlying mechanism is still unclear and …

Potential and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for acute/chronic kidney disease

CW Yun, SH Lee - International journal of molecular sciences, 2019 - mdpi.com
Kidney disease can be either acute kidney injury (AKI) or chronic kidney disease (CKD) and
it can lead to the development of functional organ failure. Mesenchymal stem cells (MSCs) …

Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury

VR Burst, M Gillis, F Pütsch, R Herzog… - Nephron Experimental …, 2010 - karger.com
Background: Although renal tubular epithelium has a great capacity for repair it has been
suggested that the administration of mesenchymal stem cells may accelerate the recovery …

Mesenchymal stem cell therapy for chronic renal failure

SJ Choi, JK Kim, SD Hwang - Expert opinion on biological therapy, 2010 - Taylor & Francis
Importance of the field: Chronic kidney disease (CKD) has become a worldwide public
health problem. Renal transplantation is the treatment of choice for end-stage renal disease …

Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury

P Semedo, PM Wang, TH Andreucci… - Transplantation …, 2007 - Elsevier
BACKGROUND: Ischemia and reperfusion injury (I/R) is the major cause of acute renal
failure (ARF) with high mortality rates. Because alternative therapies are needed, we …