Pathological alteration and therapeutic implications of sepsis-induced immune cell apoptosis
C Cao, M Yu, Y Chai - Cell death & disease, 2019 - nature.com
Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host
response to infection that leads to uncontrolled inflammatory response followed by …
response to infection that leads to uncontrolled inflammatory response followed by …
Insights into the apoptotic death of immune cells in sepsis
Y Luan, Y Yao, X Xiao, Z Sheng - Journal of Interferon & Cytokine …, 2015 - liebertpub.com
Sepsis with subsequent multiple-organ dysfunction is a distinct systemic inflammatory
response to concealed or obvious infection, and it is a leading cause of death in intensive …
response to concealed or obvious infection, and it is a leading cause of death in intensive …
[HTML][HTML] Simultaneous activation of apoptosis and inflammation in pathogenesis of septic shock: a hypothesis
VD Joshi, DV Kalvakolanu, AS Cross - FEBS letters, 2003 - Elsevier
Sepsis, a widely prevalent disease with increasing morbidity and mortality, is thought to
result from uncontrolled inflammatory responses to microbial infection and/or components …
result from uncontrolled inflammatory responses to microbial infection and/or components …
Role of apoptotic cell death in sepsis
RS Hotchkiss, KW Tinsley, IE Karl - Scandinavian journal of …, 2003 - Taylor & Francis
Sepsis is the leading cause of morbidity and mortality in critically ill patients in many
intensive care units. The pathophysiology of organ failure and death in patients with sepsis …
intensive care units. The pathophysiology of organ failure and death in patients with sepsis …
The “Self-sacrifice” of ImmuneCells in sepsis
X Wen, B Xie, S Yuan, J Zhang - Frontiers in immunology, 2022 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by the host's malfunctioning response
to infection. Due to its high mortality rate and medical cost, sepsis remains one of the world's …
to infection. Due to its high mortality rate and medical cost, sepsis remains one of the world's …
Immune dysregulation in sepsis: experiences, lessons and perspectives
M Cao, G Wang, J Xie - Cell Death Discovery, 2023 - nature.com
Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulated host
responses to infection. Not only does sepsis pose a serious hazard to human health, but it …
responses to infection. Not only does sepsis pose a serious hazard to human health, but it …
Apoptosis and caspases regulate death and inflammation in sepsis
RS Hotchkiss, DW Nicholson - Nature Reviews Immunology, 2006 - nature.com
Although the prevailing concept has been that mortality in sepsis results from an unbridled
hyper-inflammatory cytokine-mediated response, the failure of more than 30 clinical trials to …
hyper-inflammatory cytokine-mediated response, the failure of more than 30 clinical trials to …
Sepsis: inflammation is a necessary evil
Sepsis is one of the leading causes of deaths world-wide and yet there are no therapies
available other than ICU treatment. The patient outcome is determined by a complex …
available other than ICU treatment. The patient outcome is determined by a complex …
Apoptosis in sepsis
R Mahidhara, TR Billiar - Critical care medicine, 2000 - journals.lww.com
Sepsis demonstrates a marked dysregulation of the immune system in its ability to fight
infection. Previous models have focused on the mechanisms which upregulate and sustain …
infection. Previous models have focused on the mechanisms which upregulate and sustain …
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