Incidentally discovered medullary thyroid cancer: diagnostic strategies and treatment

SR Ahmed, DW Ball - The Journal of Clinical Endocrinology & …, 2011 - academic.oup.com
Context: Medullary thyroid carcinoma (MTC) is diagnosed only after thyroidectomy in
approximately 10–15% of cases. This delay in diagnosis can have adverse consequences …

The prevalence of occult medullary thyroid carcinoma at autopsy

LA Valle, RT Kloos - The Journal of Clinical Endocrinology & …, 2011 - academic.oup.com
Context: The prevalence of occult medullary thyroid carcinoma (MTC) in the general
population is unknown but may be important when considering strategies to diagnose …

Screening for medullary thyroid carcinoma with serum calcitonin measurements in patients with thyroid nodules in the United States and Canada

GH Daniels - Thyroid, 2011 - liebertpub.com
Background: Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy with the
potential for aggressive behavior. Measurement of serum calcitonin (Ct) in the thyroid …

Medullary thyroid carcinoma without marked elevation of calcitonin: a diagnostic and surveillance dilemma

TS Wang, IT Ocal, JA Sosa, H Cox, S Roman - Thyroid, 2008 - liebertpub.com
Calcitonin is a sensitive tumor marker for medullary thyroid cancer (MTC) and is useful in
preoperative diagnosis and postoperative surveillance for recurrent disease. Calcitonin …

Medullary thyroid cancer diagnosis: an appraisal

P Trimboli, L Giovanella, A Crescenzi… - Head & …, 2014 - Wiley Online Library
Since its first description in 1951, a timely diagnosis of medullary thyroid carcinoma (MTC)
may represent a diagnostic challenge in clinical practice. Several contributions have been …

Early diagnosis of medullary thyroid carcinoma: is systematic calcitonin screening appropriate in patients with nodular thyroid disease?

G Costante, S Filetti - The oncologist, 2011 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Compare guideline recommendations regarding the use of routine calcitonin screening to …

Normal preoperative calcitonin levels do not always exclude medullary thyroid carcinoma in patients with large palpable thyroid masses

AH Redding, SN Levine, MR Fowler - Thyroid, 2000 - liebertpub.com
Medullary thyroid carcinoma (MCT) is a sporadic or familial tumor of the parafollicular or C-
cells that secretes calcitonin. The sporadic form usually presents with a palpable thyroid …

A cut‐off value of basal serum calcitonin for detecting macroscopic medullary thyroid carcinoma

H Kwon, WG Kim, YM Choi, EK Jang… - Clinical …, 2015 - Wiley Online Library
Objective Serum calcitonin (CT) level is used to detect medullary thyroid carcinoma (MTC),
but the cut‐off level is unclear. We aimed at identifying the optimal cut‐off value of basal …

[HTML][HTML] Update on calcitonin screening for medullary thyroid carcinoma and the results of a retrospective analysis of 12,984 patients with thyroid nodules

M Broecker-Preuss, D Simon, M Fries, E Kornely… - Cancers, 2023 - mdpi.com
Simple Summary Medullary thyroid carcinoma (MTC) is a rare disease and accounts for
about 5% of thyroid carcinomas. In contrast to other thyroid cancers, MTC can be detected …

Serum calcitonin negative medullary thyroid carcinoma: a systematic review of the literature

P Trimboli, L Giovanella - Clinical Chemistry and Laboratory …, 2015 - degruyter.com
Generally, calcitonin (CT) values below the upper reference limit rule-out medullary thyroid
carcinoma (MTC) with very high accuracy. However, sparse cases of serum-calcitonin …